CAP Trial - Caffeine for Apnea of Prematurity Trial |
PT0357 |
Peter Davis |
Recruitment complete
|
Newborn respiratory |
|
|
N3RO - Can omega 3 fatty acids improve respiratory outcomes in preterm infants? |
ACTRN12612000503820 |
Women's & Children's Health Research Institute carmel.collins@health.sa.gov.au |
Recruitment complete
IMPACT reviewed
|
Newborn respiratory |
Born at less than 29 weeks gestational age, within 3 days of commencing enteral feeds |
|
HINT Trial - High-flow nasal cannulae versus ambient oxygen for the treatment of newborn infants with early respiratory distress in non-tertiary special care nurseries: a multicentre, randomised controlled trial |
ACTRN12611000233921 |
Gosford Hospital and The Royal Women's, Melbourne abuckmaster@nsccahs.health.nsw.gov.au |
Discontinued
|
Newborn respiratory |
|
|
CureNeb - Aerosolized surfactant in the first hour of life |
ACTRN12610000857000 |
King Edward Memorial Hospital Dr Stefan Minocchieri/Prof J J Pillow |
Discontinued
|
Newborn respiratory |
|
|
Flows at Lower Rates (FLoRa) - Is bias gas flow in ventilated preterm babies related to lung injury and risk of bronchopulmonary dysplasia? |
ACTRN12611000628943 |
Liggins Institute, University of Auckland kittyb@adhb.govt.nz; f.bloomfield@auckland.ac.nz |
Discontinued
|
Newborn respiratory |
Babies born at < 28 weeks’ or < 1,000 g needing ventilation in first week of life |
|
High flow support versus continuous positive airway pressure (CPAP) support in non-acute respiratory support for preterm infants from 30 weeks corrected gestation |
ACTRN12610000677000 |
Ashley McEwan: ashley.mcewan@hotmail.com |
Recruitment complete
|
Newborn respiratory |
|
|
DINO trial - Docosahexaenoic acid (DHA) for the improvement of neurodevelopmental outcome in preterm infants |
PT0424/NHMRC250322/ACTRN12606000327583 |
Women's and Children's Hospital Suzanne McCusker |
Recruitment complete
|
Newborn nutrition. Newborn ? developmental |
Infants born < or = 32 weeks gestation |
|
Effect of position during bottle feeding on physiological stability in preterm infants |
ACTRN12611000944932 |
Dr Jennifer Dawson |
Recruitment complete
|
Newborn nutrition |
|
|
Efficacy and safety of a novel fish oil based lipid emulsion (SMOFlipid) compared with olive oil based lipid emulsion (Clinoneic) in term and near-term (>34 weeks) neonates - a randomised controlled trial |
ACTRN12609000337279 |
Princess Margaret Hospital for Children, WA girish.deshpande@health.wa.gov.au |
Recruitment complete
|
Newborn nutrition |
|
|
IFOS - The Infant Fish Oil Supplementation Study |
ACTRN12606000281594 |
Princess Margaret Hospital
S J Meldrum |
Recruitment complete
|
Newborn nutrition |
|
|
Tolerability and safety of olive oil-based lipid emulsion in critically ill neonates: a blinded randomized trial |
|
julie.bines@rch.org.au |
Recruitment complete
|
Newborn nutrition |
|
|
Selenium status of term infants fed selenium-supplemented formula in a randomized dose-response trial |
|
Maria Makrides |
Recruitment complete
|
Newborn nutrition |
|
|
TIGGA - Growth and nutritional status of infants fed formula based on goat milk or cow milk |
ACTRN12608000047392 |
Child Nutrition Research Women's & Children's Hospital Jo Zhou |
Recruitment complete
|
Newborn nutrition |
Healthy term infants, birth weight >=2.5kg & <=4.75kg, mother is exclusively feeding an infant formula within 2 weeks of birth or plans to exclusively breastfeed for at least 4 months. |
|
POPPET - Providing Optimal Protein for Prems via Enteral Tubes. Does increasing the protein content of human milk fortifier improve growth in preterm infants <33 weeks gestation? A randomised controlled trial. |
ACTRN12611001275954 |
Women's & Children's Health Research Institute jessica.reid@adelaide.edu.au |
Recruitment complete
|
Newborn nutrition |
Infants <33 completed weeks gestation whose mothers intend to provide breast milk |
|
Safety of supplementing infant formula with long-chain polyunsaturated fatty acids and Bifidobacterium lactis in term infants: a randomised controlled trial |
|
Women's & Children's Hospital, CYWHS Maria Makrides |
Recruitment complete
|
Newborn nutrition |
|
|
InFANT - The Infant Feeding Activity and Nutrition Trial an early intervention to prevent childhood obesity: cluster-randomised controlled trial |
ISRCTN81847050 |
Melbourne Dr Karen Campbell |
Recruitment complete
|
Newborn nutrition |
|
|
SUPPOSE - Randomised controlled trial of prophylactic glycerol suppositories on gastric emptying and feed tolerance in premature infants |
|
|
Recruitment complete
|
Newborn nutrition |
|
|
DINO-II pilot study - Determining the docosahexaenoic acid dose to obtain plasma and erythrocyte phospholipid fatty acid profiles in preterm infants comparable to term infant profiles: a dose response pilot study. |
ACTRN12610000382077 |
carmel.collins@health.sa.gov.au |
Recruitment complete
|
Newborn nutrition |
Infants born less than 33 weeks gestation after one but before five days of commencing any enteral feeds and with parental/guardian consent. Multiple births will be eligible and will be randomised individually. Women providing breast milk for their infant not taking DHA supplements or willing to stop taking supplements for duration study. |
|
ProPrem - The use of probiotics to reduce the incidence of sepsis in premature infants |
ACTRN12607000144415 |
Royal Women's Hospital Linh Ung |
Recruitment complete
|
Newborn infection. Newborn nutrition |
|
|
INIS - International Neonatal Immunotherapy Study |
ACTRN012606000273583; NHMRC301973; PTO373 |
Westmead Hospital, NSW Priya Duggal-Beri |
Recruitment complete
|
Newborn infection |
|
|
LOS trial - Prevention of late onset septicemia in infants in the neonatal intensive care unit, Mater Mothers' Hospital. |
PT0363 |
Mater Mothers' Hospital, Brisbane Helen Liley |
Recruitment complete
|
Newborn infection |
|
|
Randomised control trial comparing the use of the Neobar endotracheal tube holder with standard taping technique for nasal intubation in the newborn infant |
|
Kristen James |
Recruitment complete
|
Newborn cardiovascular |
|
|
DETECT - Targeting of treatment of the patent ductus arteriosus using early echocardiography |
ACTRN12608000295347 |
martin.kluckow@sydney.edu.au |
Recruitment complete
|
Newborn cardiovascular |
|
|
Randomised trial of dopamine vs dobutamine for treatment of low systemic blood flow in very preterm infants |
ACTRN12607000152426 |
Nick Evans |
Recruitment complete
|
Newborn cardiovascular |
|
|
Targeting duration of indomethacin treatment to the PDA constrictive response using echocardiography: a randomised controlled trial |
|
|
Recruitment complete
|
Newborn cardiovascular |
|
|
OPIO - Optimising preterm infant outcomes: a RCT to evaluate two screening & surveillance methods |
PT0518/ACTRN012606000472572 |
Margo Pritchard |
Recruitment complete
|
Newborn ? developmental |
|
|
Help-seeking for postnatal depression as a major public health problem: A cluster randomised controlled trial of motivational interviewing |
ACTRN12611000635965 |
Parent-Infant Research Institute, Austin Health, (03) 9496 4496, piri@austin.org.au
|
Recruitment complete
|
Motivational interviewing, postnatal depression |
Women with a 4-week old baby |
|
OPRA - Outpatient cervical priming for induction of labour |
ACTRN12608000249358 |
Women's and Children's Hospital chrisswilkinson@mac.com |
Recruitment complete
|
Models of care. Labour and intrapartum care |
Pregnant women having priming for induction of labour, where induction is clinically indicated, there is no evidence of maternal or fetal compromise and in the opinion of the referring caregiver, outpatient management and monitoring is clinically appropriate |
|
MANGO - A randomised controlled trial of caseload midwifery |
ACTRN12609000349246 |
UTS |
Recruitment complete
|
Models of care. |
Pregnant women will be eligible if they are: 18 years of age or older, at 24 weeks of gestation, currently experiencing a mood disorder and have a Edinburgh Postnatal Depression Scale (EPDS) scores of greater than or equal to 13. |
|
COSMOS - Caseload midwifery for women at low risk of medical complications: a randomised controlled trial |
ACTRN12607000073404 |
Royal Women's Hospital Helen McLachlan |
Recruitment complete
|
Models of care |
|
|
EECV2 - Early external cephalic version 2 trial |
PT0542/ISRCTN56498577 |
McMaster, Canada Eileen Hutton |
Recruitment complete
|
Models of care |
|
|
The effects of mindfulness training on maternal stress, depressed mood and present moment awareness: A pilot randomised trial |
ACTRN12614000523606 |
Monash University jill.beattie@monash.edu |
Recruitment complete
|
Mindfulness, Pregnancy, Randomised trial |
Low risk pregnancy in the second trimester at the start of the intervention; 18 years or older; able to read and speak English; having a planned hospital birth; and who commit to attending all eight sessions. |
|
The DOMInO Trial - Randomised Trial of DHA in pregnancy to prevent postnatal depressive symptoms and enhance neurodevelopment in children |
ACTRN12611001125910/NHMRC 349301 |
Children, Youth and Women's Health Services, SA Suzanne McCusker |
Recruitment complete
|
Maternal nutrition. Parental social and emotional wellbeing |
Children who were included in the secondary outcome (neurodevelopment at 18months as assessed by the BSIDIII) of the original DOMInO Trial |
|
GI Baby 3 - A dietary intervention during pregnancy to reduce child obesity |
ACTRN12610000681055 |
The University of Sydney Dawn Tan |
Recruitment complete
|
Maternal nutrition. Obesity |
|
|
EASI - Efficacy and side effects of iron supplements for the correction of anaemia in pregnant women: a comparison of high dose vs low dose iron |
PT0538 / ACTRN12606000357550 |
WCH Maria Makrides |
Recruitment complete
|
Maternal nutrition. Maternal medical conditions |
Pregnant women with anaemia on routine screening test at the end of 2nd trimester |
|
The effect of a low glycemic index diet during pregnancy on obstetric outcomes |
|
JC Brand Miller |
Recruitment complete
|
Maternal nutrition |
|
|
AMBIT - Australian Mothers and Babies Iron Trial |
NHMRC250431 |
Maria Makrides |
Recruitment complete
|
Maternal nutrition |
|
|
DHAllergy - Fish oil supplementation in pregnancy to reduce allergies in early childhood |
ACTRN12610000735055 |
Child Nutrition Research Centre, Women's & Children's Health Research Inst, WCH Debbie Palmer |
Recruitment complete
|
Maternal nutrition |
Child to have a family history of medically diagnosed allergic disease (eczema, asthma, allergic rhinitis): singleton pregnancy less than 18-21 weeks gestation with no known fetal abnormality: mothers not to have had documented history of alcohol or drug abuse: no participation in other clinical trials with fatty acid intervention. |
|
PREGGIO - Pregnancy and Glycaemic Index Outcomes Study comparing a low glycaemic index (GI) diet to a standard healthy diet |
ACTRN12610000174088 |
Clinical Trials & Research Unit South East Sydney & Illwarra Area Health Service Diabetes Centre Shelly Charters |
Recruitment complete
|
Maternal nutrition |
|
|
Effect of maternal egg consumption on breast milk ovalbumin concentration |
|
Women's & Children's Hospital |
Recruitment complete
|
Maternal nutrition |
|
|
A prospective randomised trial to study the effect of intravenous iron therapy versus the standard treatment with oral iron for women diagnosed with iron deficiency anaemia in pregnancy |
ACTRN12609000177257 |
Launceston General Hospital
joanne.bates@dhhs.tas.gov.au |
Recruitment complete
|
Maternal nutrition |
At risk women - dark skinned, veiled, Anyone with vitamin D deficiency that has not commenced treatment prior to recruitment |
|
A randomised controlled trial on the effects of antenatal vitamin D supplementation to improve vitamin D levels in the maternal and cord blood at birth in vitamin D deficient pregnant women |
ACTRN12609000142235 |
Monash Medical Centre |
Recruitment complete
|
Maternal nutrition |
|
|
CHIPS trial: Control of Hypertension In Pregnancy Study |
ISRCTN71416914 / NCT01192412 |
|
Recruitment complete
|
Maternal medical conditions. Preeclampsia |
|
|
PRAM - Prospective Randomised Automated versus Mercury blood pressure recordings in hypertensive pregnancy |
NCT00809666 |
University of Sydney Lynne Roberts |
Recruitment complete
|
Maternal medical conditions |
|
|
Hypnosis for nausea and vomiting in early pregnancy a randomised controlled trial |
ACTRN12607000127404 |
Women's and Children's Hospital Alan Cyna alan.cyna@adelaide.edu.au |
Recruitment complete
|
Maternal medical conditions |
Pregnant women suffering from nausea and vomiting of pregnancy. |
|
MAMMA -Multidisciplinary Approach to Management of Maternal Asthma |
ACTRN12612000681853 |
Mercy Hospital for Women<br>Monash University Johnson.George@monash.edu |
Recruitment complete
|
Maternal medical conditions |
|
|
World Maternal Antifibrinolytic Trial (WOMAN) - Tranexamic acid for the treatment of postpartum haemorrhage: an international, randomised, double blind, placebo controlled trial. |
ISRCTN76912190/ NCT00872469 |
Clinical Trials Unit, London School of Hygiene and Tropical Medicine
thewomantrial@lshtm.ac.uk, http://www.womantrial.lshtm.ac.uk/
|
Recruitment complete
|
Maternal Health, Postpartum Haemorrhage |
Adult women, after delivery who have clinically diagnosed postpartum haemorrhage, are eligible if the responsible doctor is for any reason substantially uncertain whether or not to use an antifibrinolytic agent. 20 060 women were enrolled by the end of the trial. |
|
The Colic, Irritability, Reflux, Intolerance and Allergy Study (CIRIAS) |
ACTRN12612000773831 |
University of Queensland, South Brisbane,Tracy Harb, t.harb@uq.edu.au |
Recruitment complete
|
maternal dietary intervention for colic |
Mothers of fully breastfed infant <4 months of age with colic |
|
DRESSING Trial - ADding negative pRESSure to improve healING in obese women undergoing caesarean section - PILOT |
ACTRN12612000171819 |
Griffith University w.chaboyer@griffith.edu.au |
Recruitment complete
|
Labour and intrapartum care. Obesity |
|
|
ACTOTTAB - Twins: Timing of birth at Term |
PT0426/ISRCTN15761056 |
WCH, Adelaide Jodie Dodd |
Recruitment complete
|
Labour and intrapartum care. Models of care |
Women with a twin pregnancy at 37 weeks gestation |
|