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Trial Name Trial ID Main Coordinating Centre
and contact		 Status Recruitment Topic Participants Details
In extremely low birth weight (ELBW) infants who require positive pressure at birth does the Neopuff Infant Resuscitator compared with the Laerdal Infant bag improve oxygen saturation measurements in the first 10 minutes of life? Resuscitation Trial ACTRN12607000062426 Jennifer Dawson Recruitment complete
Less MAS - Controlled trial of therapeutic lung lavage in meconium aspiration syndrome ACTRN12606000290594/PT0535 Royal Hobart Hospital, Tas Bev Copnell Recruitment complete
FOG Trial - Outpatient Foley catheter vs inpatient Prostin gel for induction of labour ACTRN12609000420246 Royal Hospital for Women amanda.henry@sesiahs.health.nsw.gov.au Recruitment complete Labour and intrapartum care
Oral misoprostol versus intravenous oxytocin for induction of labour following artificial or spontaneous rupture of membranes jodie.dodd@adelaide.edu.au Recruitment complete Labour and intrapartum care Women > or = 41 weeks booked for delivery at Women's and Children's Hospital; singleton pregnancy; cephalic presentation
CiPS - Candida in Pregnancy Study - Treatment of candidiasis to prevent preterm birth - pilot study CiPS pilot ACTRN126090001052224 Royal North Shore Recruitment complete Preterm birth ? prevention and treatment
Positioning to improve lung function in preterm infants requiring ventilatory support ACTRN12606000210572 judith.hough@mater.org.au Recruitment complete
PDA Trial - Paracetamol Duct Action: The effect of paracetamol vs placebo on ductal closure in premature infants with a late patent ductus arterious ACTRN12611000741987 Royal North Shore Hospital, NSW Prof Martin Kluckow martin.kluckow.usyd.edu.au Recruitment complete PDA closure, Preterm infant, Paracetamol Population: Preterm infants born <33 weeks gestational age with a persistent PDA who are >4 weeks of postnatal age and tolerating at least 50% enteral feeds.
The effect of active chest physiotherapy techniques on regional ventilation on preterm infants on ventilatory support ACTRN12606000211561 Judy Hough Recruitment complete
A comparison of Propofol and Suxamethonium as induction agents for neonatal endotracheal intubation PT0545 Julee Oei Recruitment complete Newborn respiratory. Newborn resuscitation
Effect of different diets on gestational diabetes. Can a low glycemic index (GI) diet during pregnancy reduce prevalence of large for gestation age (LGA) amongst gravidas with gestational diabetes (GDM) - a randomised controlled trial ACTRN12608000218392 Royal Prince Alfred Hospital Recruitment complete Diabetes. Maternal nutrition
Fighting obesity from conception- a randomised trial ACTRN12605000709640; PT0543 Julie Quinlivan Recruitment complete Obesity. Maternal nutrition
Tolerability and safety of olive oil-based lipid emulsion in critically ill neonates: a blinded randomized trial julie.bines@rch.org.au Recruitment complete Newborn nutrition
Efficacy of an oral health promotion intervention in the prevention of early childhood caries Kamila Plutzer Recruitment complete
POP-OUT - Persistent Occiput Posterior: OUTcomes following manual rotation ACTRN12612001312831 Royal Prince Alfred Hospital, NSW hala.phipps@email.cs.nsw.gov.au Recruitment complete
IMPACT reviewed
 Labour and intrapartum care
Phototherapy and Patency of the Ductus Arteriosus in Extremely Preterm infants: A randomised Trial Karen Simmer Recruitment complete
A double blind randomised controlled trial comparing the efficacy and safety of an olive oil based lipid emulsion (Clinoleic) to a soybean oil based lipid emulsion (Intralipid) in very preterm infants requiring parenteral nutrition Karen Simmer Recruitment complete
Perineal outcomes and maternal comfort related to the application of perineal warm packs in the second stage of labor: a randomised controlled trial Royal Prince Alfred Women and Babies, NSW Recruitment complete Labour and intrapartum care
BAMBINO - A randomized controlled trial using exercise to reduce gestational diabetes and other adverse maternal and neonatal outcomes in obese pregnant women - the pilot study ACTRN12606000271505 Katie Foxcroft katie_foxcroft@health.qld.gov.au Recruitment complete
FLAMINGO Trial - Fetal lactate measurement to reduce caesarean sections during labour: a randomised trial ACTRN12611000172909 Royal Women`s Hospital, Vic christine.east@monash.edu Recruitment complete Labour and intrapartum care
Dose-effect study of domperidone as a galactagogue in preterm mothers with insufficient milk supply, and its transfer into milk ken.ilett@uwa.edu.au Recruitment complete Breastfeeding
COSMOS - Caseload midwifery for women at low risk of medical complications: a randomised controlled trial ACTRN12607000073404 Royal Women's Hospital Helen McLachlan Recruitment complete Models of care
AC/VG Flow Study - Ventilator circuit flow selection during neonatal assist control volume guarantee ventilation: a randomised crossover trial. ACTRN12610000885099 Kevin Wheeler Recruitment complete Newborn respiratory
ProPrem - The use of probiotics to reduce the incidence of sepsis in premature infants ACTRN12607000144415 Royal Women's Hospital Linh Ung Recruitment complete Newborn infection. Newborn nutrition
AC/VG Pmax Study - Pressure limit selection during neonatal assist control volume guarantee ventilation: A randomised crossover trial. ACTRN12610000886088 kevin.wheeler@thewomens.org.au Recruitment complete Newborn respiratory
DART Trial - Postnatal Dexamethasone in tiny babies: does it do more good than harm? PT0359/NHMRC108700 Royal Women's Hospital Melbourne Lex Doyle Recruitment complete
The effect of sildenafil in preterm infants with evolving chronic lung disease NCT00431418 kkonig@mercy.com.au Recruitment complete Newborn respiratory
COIN Trial: Nasal CPAP (continuing positive airways pressure) or intubation for very preterm infants at birth. A randomised controlled trial PT0368/ACTRN012606000258550 Royal Women's Hospital, Melbourne Colin Morley Recruitment complete
Randomised control trial comparing the use of the Neobar endotracheal tube holder with standard taping technique for nasal intubation in the newborn infant Kristen James Recruitment complete Newborn cardiovascular
HIPERSPACE - Comparing the failure rate of high-flow nasal cannulae (HFNC) versus nasal continuous positive airway pressure (CPAP) as post-extubation respiratory support in premature infants with gestational age of 24 to 32 weeks. ACTRN12610000166077 Royal Women's Hospital, Vic Dr Brett Manley Recruitment complete Newborn respiratory
Postnatal Perineal Pain Project ACTRN12609000555257 Kristen Rickard Recruitment complete
AC/VG BUR Study - Backup rate selection during neonatal assist control volume guarantee ventilation: a randomised crossover trial. ACTRN12610000884000 Royal Women's Hospital
kevin.wheeler@thewomens.org.au		 Recruitment complete Newborn respiratory
VIBES PLUS - A randomised trial of preventative care at home in very preterm infants on neurosensory outcome at 2 years of age ACTRN12605000492651 Royal Women's Hospital, Vic Lex Doyle Recruitment complete
REPIT - A Randomised trial of an early parenting intervention to reduce maternal mood disorder and infant behaviour disturbance ACTRN12606000063516 Lauren Matheson Recruitment complete
A randomised controlled trial of the effect of physiotherapy intervention on pelvic floor dysfunction in postpartum women PT0514 Laurie Breheny Recruitment complete
Early intervention of multiple home visits to prevent childhood obesity among a disadvantaged population : a home-based randomised controlled trial Healthy Beginnings ACTRN120607000168459 Li Ming Wen Recruitment complete
Evaluating the impact of the Belly Bra on back pain in pregnancy ACTRN12605000270617 Louise Kornman Recruitment complete
The effects of nasal continuous positive airway pressure on cardiac function in (i) premature infants with established lung disease and (ii) premature infants with minimal lung disease. ACTRN12611001057976 Royal Women's Hospital, Vic sheryle.rogerson@the womens.org.au Recruitment complete Newborn respiratory. Newborn cardiovascular
HiFloW Trial - A randomised controlled trial to evaluate the effectiveness of heated, humidified high flow nasal cannula (HHHFNC) in the withdrawal of nasal continuous positive airway pressure (nCPAP) in preterm infants ACTRN12610001003066 RPA Hospital, Sydney david.osborn@email.cs.nsw.gov.au Recruitment complete Newborn respiratory
Telephone reminders to improve the follow-up rate for neonatal intensive care graduates M J Ross Recruitment complete
PICOP - Use of chlorhexidine as a topical antiseptic for the prevention of nosocomial infection in premature neonates < 29 weeks: a blinded randomised controlled trial RPA Women's and Babies sandie@email.cs.nsw.gov.au Recruitment complete
Support for ongoing breastfeeding ACTRN12608000361303 Rural Clinical School, University of New South Wales megan.elliott-rudder@student.unsw.edu.au Recruitment complete Breastfeeding
OPIO - Optimising preterm infant outcomes: a RCT to evaluate two screening & surveillance methods PT0518/ACTRN012606000472572 Margo Pritchard Recruitment complete Newborn ? developmental
STINT - Does the use of an introducer (stylet) improve the success rate at orotracheal intubation in newborn infants ACTRN12607000186459 RWH, Vic Liam O'Connell Recruitment complete
AMBIT - Australian Mothers and Babies Iron Trial NHMRC250431 Maria Makrides Recruitment complete Maternal nutrition
Helping indigenous women to stop smoking during pregnancy NHMRC320851; ACTRN12609000929202 Sax Institute Sandra Eades Recruitment complete Indigenous maternal/perinatal health. Smoking in pregnancy
Dietary nucleotide supplementation Maria Makrides Recruitment complete
VITAL Trial - The effects of vitamin D supplementation in infancy on immune development ACTRN12612000787886 Childhood Allergy and Immunology Research, University of Western Australia, Dr Debbie Palmer, Ph: + 61 410 851 607, debbie.palmer@uwa.edu.au
 Recruitment complete Vitamin D, infants, immune development Infants with a family history of allergic disease
Selenium status of term infants fed selenium-supplemented formula in a randomized dose-response trial Maria Makrides Recruitment complete Newborn nutrition
DETECT - Targeting of treatment of the patent ductus arteriosus using early echocardiography ACTRN12608000295347 martin.kluckow@sydney.edu.au Recruitment complete Newborn cardiovascular
Furosemide for packed red cell transfusion in preterm infants: a randomized controlled trial martin.kluckow@sydney.edu.au Recruitment complete