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Trial Name Trial ID Main Coordinating Centre
and contact		 Status Recruitment Topic Participants Details
OPTIMIST-A - Multicentre randomised controlled trial of minimally-invasive surfactant therapy in preterm infants 25-28 weeks gestation on continuous positive airway pressure ACTRN12611000916943 : NCT02140580 Menzies Institute, UTAS (optimist.trial@utas.edu.au) Currently recruiting Minimally-invasive surfactant therapy, preterm infant, respiratory distress syndrome Preterm infants 25-28 weeks gestation on CPAP
Candida in Pregnancy Study (CiPS) - Treatment of asymptomatic candidiasis in pregnant women for the prevention of preterm birth NHMRC 632532; ACTRN12610000607077 Royal North Shore Hospital krrickar@nsccahs.health.nsw.gov.au Currently recruiting
APProve: CAn Probiotics ImPROVE Breastfeeding Outcomes? ACTRN12615000923561 Royal North Shore Hospital, St Leonards natasha.nassar@sydney.edu.au Currently recruiting
POT-OUT Study - Persistent Occiput Transverse: OUTcomes following manual rotation. ACTRN12613000005752 Royal Prince Alfred Hospital, NSW hala.phipps@sswahs.nsw.gov.au Currently recruiting Labour and intrapartum care
Post partum hypertension risk after non-steroidal analgesic use (excluding paracetamol) PT0522 Royal Prince Alfred Hospital, NSW<br>Campbelltown Hospital, NSW ahennes@renal.rpa.cs.nsw.gov.au Currently recruiting
Oropharyngeal airway for prevention of airway obstruction during positive pressure ventilation in preterm infants < 34 weeks gestation during neonatal resuscitation - a randomised trial ACTRN12612000392864 Royal Women's Hospital, Vic omar.kamlin@thewomens.org.au Currently recruiting
In very preterm infants who are being extubated to nasal continuous positive airway pressure (CPAP), does a continuous positive airway pressure (CPAP) recruitment maneuvre post extubation improve global and regional end-expiratory lung volume CPAP Study ACTRN12610000167066 Royal Women's Hospital, Vic risha.bhatia@thewomens.org.au Currently recruiting Newborn respiratory
The SYMBA Study - Promoting gut health (symbiosis) with prebiotic fibre for prevention of allergic disease ACTRN12615001075572 Joondalup Health Campus, Dr Debbie Palmer debbie.palmer@uwa.edu.au Currently recruiting Allergy prevention, Maternal diet prebiotic supplementation
Pregnant women whose infants have a first-degree relative (mother, father or sibling) with a history of medically diagnosed allergic disease (asthma, allergic rhinitis, eczema and/or food allergy)
MobileMums - Helping women with young children meet their physical activity goals: a randomised, controlled trial of a personalised program delivered by mobile telephone text messaging ACTRN12611000481976 School of Public Health, Queensland University of Technology alison.marshall@qut.edu.au; jasmine.obrien@qut.edu.au Currently recruiting
Capacity for informed consent during labour ACTRN12614000456651 School of Women's and Children's Health, UNSW, Royal Hospital for Women amanda.henry@unsw.edu.au Currently recruiting
A randomised control trial comparing two methods of delivering continuous positive airway pressure (CPAP), infant flow system CPAP and bubble CPAP, in supporting successful extubation for infants of birth weights less than or equal to 1500 grams at birth ACTRN12605000400662/NCT00187434 Sunnybrook Health Sciences Centre, Canada marilyn.hyndman@sw.ca Currently recruiting
Epidural pain relief and the outcome of labour ACTRN12614000448640 Sydney Medical School Nepean, The University of Sydney hall6a3@hotmail.com Currently recruiting
AAMS - Antenatal Asthma Management Service ACTRN12613000244707 The Robinson Institute, University of Adelaide
vicki.clifton@adelaide.edu.au		 Currently recruiting Participants must be less than 18 weeks gestation with a singleton pregnancy, have asthma which has been previously diagnosed by a doctor and is not currently in remission (remission defined as no asthma symptoms and no use of asthma medications in previous year), aged 18-45 years,
PKE - Evaluating a new parenting kit developed by the Royal Women?s Hospital: a mixed methods study ACTRN12615000270516 The Royal Women's Hospital d.forster@latrobe.edu.au Currently recruiting
HUMID Study - A comparison of humidified and unconditioned gases in the delivery room for stabilising preterm infants less than 30 weeks gestation at birth ACTRN12613000093785 The Royal Women's Hospital, Vic lorraine.mcgrory@thewomens.org.au Currently recruiting Newborn resuscitation
OPTIMISE - Optimising gestational weight gain and improving maternal and infant health outcomes through antenatal dietary, lifestyle and exercise advice, the randomised trial ACTRN12614000583640 The University of Adelaide jodie.dodd@adelaide.edu.au Currently recruiting Women with a singleton, live gestation between 10+0-20+0 weeks who are of normal BMI (defined as a BMI 18.5-24.9kg/m2), at the time of the first antenatal visit.
TARGET - Optimal glycaemic targets for gestational diabetes: the randomised trial ACTRN12615000282583 Liggins Institute, target@auckland.ac.nz Currently recruiting Gestational diabetes, glycemic control, birthweight Women with gestational diabetes
GEMS - Gestational diabetes trial of detection thresholds: Impact on health and costs ACTRN12615000290594 Liggins Institute, GEMS@auckland.ac.nz Currently recruiting Gestational diabetes, diagnostic thresholds, birthweight Women at >24 weeks’ gestation having a oral glucose tolerance test for gestational diabetes
Oxytocin as an adjunct to interaction coaching and baby massage to improve bonding in the early postpartum ACTRN12609000483257 The University of New South Wales rmcerlean@psy.unsw.edu.au Currently recruiting Parenting
HINT 2 - Hyperglycaemia in Neonates Trial. Computer determined insulin dosage in the management of neonatal hyperglycaemia ACTRN12614000492651 University of Auckland; Department of Paediatrics: Child and Youth Health, Jane Alsweiler, j.alsweiler@auckland.ac.nz Currently recruiting Neonatal hyperglycaemia, Insulin
 Extremely preterm babies with neonatal hyperglycaemia
WENDY - Walking for Exercise and Nutrition to prevent Diabetes for You ACTRN12611000075987 / NCT01247753 University of Michigan & Mater Mothers Hospital apeacock@mmri.mater.org.au Currently recruiting Diabetes
A randomised control trial (RCT) of enhanced parenting to improve developmental outcomes in preterm infants ACTRN12612000194864 University of Queensland
p.colditz@uq.edu.au		 Currently recruiting Newborn developmental. Parenting
Mums Step it Up - Effectiveness of a facebook-delivered physical activity intervention for post-partum women ACTRN12613000069752 University of South Australia jocelyn.kernot@unisa.edu.au Currently recruiting
Gen-D Study - The efficacy of vitamin D supplementation in infants on bone mineral content: A double blind randomized controlled trial ACTRN12613000732785 University of Tasmania Menzies Research Institute Ingrid.vanderMei@utas.edu.au Currently recruiting
VBAC - A randomised controlled trial to determine whether continuity of care increases the rate of attempted vaginal birth after caesarean ACTRN12611001214921 University of Technology, Sydney caroline.homer@uts.edu.au Currently recruiting
TOBOGM -The Treatment Of BOoking Gestational diabetes Mellitus Pilot Study: Evaluating the impact on obstetric outcomes of immediate versus delayed care for gestational diabetes diagnosed at booking ACTRN12615000974505 University of Western Sydney da.simmons@uws.edu.au Currently recruiting Diabetes Pregnant women (aged >=18years) with a singleton pregnancy between 4 and 19+6 weeks? gestation, attending the hospital Book in clinic, with a risk factor for GDM warranting an OGTT according to ADIPS/local guidelines
PIP - A maternal probiotic intervention for infant allergic disease prevention ACTRN12612000196842 Wellington Asthma Research Group, Wellington kristin.wickens@otago.ac.nz Currently recruiting
A randomised controlled trial studying the effectiveness of mask ventilation with a 2 person method compared to a 1 person method in preterm neonates prior to non-emergent endotracheal intubation in reducing mask leak and airway obstruction ACTRN12613001216707 Westmead Hospital mark.tracy@swahs.health.nsw.gov.au Currently recruiting
Foley Catheter Latex versus Silicone for Cervical Ripening Prior to Term Induction of Labour: a randomized controlled trial ACTRN12615000795594 Westmead Hospital; Dr Terry McGee, Terry.McGee@health.nsw.gov.au Currently recruiting Latex; Silicon; Foley catheter This is a prospective randomized clinical trial that is carried out in the Day Assessment Unit and the Birth Unit (the usual sites of Foley catheter insertion) at Westmead Hospital . All women 16 years and over booked for cervical ripening with a Foley catheter before term induction of labour are asked to participate in the study.
Apart from the randomization of catheter material (latex v silicone) all other care will be identical to women not participating in the study.
COPRA - A pilot randomised controlled trial of outpatient balloon catheter priming for induction of labour ACTRN12612001184864 Women`s & Children`s Hospital chrisswilkinson@mac.com Currently recruiting Pregnancy is at term (37 completed weeks to 42 completed weeks), intact membranes, induction being performed for post-dates or social reason, singleton, appropriately grown by clinical exam, cephalic presentation. (Clinical suspicion of growth restriction investigated by ultrasound assessment). -Cervical ripening for reasons other than fetal or maternal compromise.
ORIP - Omega-3 fats to reduce the incidence of prematurity ACTRN12613001142729 Women`s and Children`s Health Research Institute, SA (WCH) jo.zhou@adelaide.edu.au Currently recruiting Preterm birth ? prevention and treatment. Maternal nutrition Women at less than 20 weeks' gestation
A RCT of pregnant women being monitored during labour with ST analysis monitoring and cardiotocography compared to being monitored with cardiotocography alone in order to reduce caesarean section whilst still having comparable outcomes for the baby. ACTRN12615001308583 Women's & Children's Hospital, Adelaide chrisswilkinson@mac.com Currently recruiting Labour and intrapartum care Women >= 18 years, gestation >36 completed weeks, expected to labour and deliver vaginally, singleton fetus, cephalic presentation, suitable for STan monitoring.
WASH*T - Effect of transfusion of washed red blood cells on neonatal outcome: a randomised controlled trial ACTRN12613000237785 Women's & Children's Hospital, SA michael.stark@adelaide.edu.au Currently recruiting Transfusion, Immunology and Neonatal Outcomes Infants born with a gestational age up to 28 weeks 6 days clinically requiring a packed red blood cell transfusion transfusion.
GluT pilot - Glucose Targets in gestational diabetes Pilot ACTRN12614001250628 Women's and Children's Hospital bill.hague@adelaide.edu.au Currently recruiting Diabetes. Maternal medical conditions Pregnant women with gestational diabetes diagnosed on 75g OGTT: fasting glucose >=5.5 mmol/L and 2h glucose >=8.5 mmol/L, between 12 and 30 weeks gestation, with a singleton or twin pregnancy, not previously diagnosed as diabetic
OptiMum - Optimising Protection for Pregnant Women with Influenza Vaccination ACTRN12614000374662 Women's and Children's Hospital Foundation helen.marshall@adelaide.edu.au Currently recruiting Pregnant women aged 18 to 40 years (inclusive) at the time of the vaccination
DIAMOND - DIfferent Approaches to MOderate & later preterm Nutrition: Determinants of feed tolerance, body composition and development ACTRN12616001199404 Liggins Institute, University of Auckland
t.alexander@auckland.ac.nz		 Currently recruiting
IMPACT endorsed
 Newborn nutrition Newborn body composition Neurodevelopment Preterm babies between 32+0 - 35+6 admitted to the neonatal unit requiring IV insertion
TASTE - Effect of smell and taste to improve nutrition in very preterm babies ACTRN12617000583347 Neonatal Critical Care Unit, Mater Mothers' Hospital, QLD 4101
Dr Friederike Beker
friederike.beker@mater.org.au		 Currently recruiting Newborn, nutrition, preterm, tube feeding Very preterm newborns
A micronutrient intervention for pregnant women experiencing symptoms of depression and anxiety ACTRN12617000354381 Mental Health and Nutrition Research Group, Department of Psychology, University of Canterbury, Christchurch 8140
Prof Julia Rucklidge
julia.rucklidge@canterbury.ac.nz		 Currently recruiting Maternal mental health, micronutrients Pregnant women
NIPA Trial (Nifedipine for improving Implantation and Pregnancy rates in ART) Does nifedipine improve implantation and pregnancy rates in women undergoing in-vitro fertilisation (IVF)/intracytoplasmic sperm injection (ICSI) cycles? ACTRN12617000213347 Melbourne IVF, East Melbourne, VIC, 3002
Dr Alex Polyakov
alex.polyakov@mivf.com.au		 Currently recruiting Reproductive medicine, IVF implantation, nifedipine Women
Efficacy of the Eating4Two smartphone application for the prevention of excessive gestational weight gain ACTRN12617000169347 University of Canberra, Bruce ACT, 2601
Prof Deborah Davis
deborah.davis@canberra.edu.au		 Currently recruiting Pregnancy, maternal weight gain, smart phone application Pregnant women
STREAM - Effect of ovarian stimulation on oocyte quality and embryonic aneuploidy: a prospective, randomised controlled trial ACTRN12616001539426 School of Women’s &amp, Children’s Health, Royal Hospital for Women, NSW 2031
Prof William Ledger
w.ledger@unsw.edu.au		 Currently recruiting Reproductive medicine, IVF, ovarian stimulation Women undergoing fertility treatment
EPAR study - Early PARacetamol (EPAR) to promote early closure of the ductus arteriosus in preterm infants ACTRN12616001517460 Department of Newborn Care, Royal Hospital for Women, Barker St, Randwick NSW 2031
Dr Timothy Schindler
tschindl@med.usyd.edu.au		 Currently recruiting Newborn, preterm, ductus arteriosus Preterm newborns
SEED (Sleep, Eat, Emotions, and Development): Enhancing sleep and wellbeing in mothers and infants ACTRN12616001462471 Monash Institute of Cognitive and Clinical Neurosciences, Sleep Program, School of Psychological Sciences, Monash University, Clayton VIC 3800
Dr Bei Bei
bei.bei@monash.edu		 Currently recruiting Maternal and infant wellbeing, sleep Pregnant women
Integrated e-Screening for Postnatal Depression and Anxiety ACTRN12616001217493 Parent-Infant Research Institute, Heidelberg Repatriation Hospital, VIC 3081
Prof Jeannette Milgrom
jeannette.milgrom@austin.org.au		 Currently recruiting Maternal mental health, postnatal depression screening Pregnant women
CRUMD - Cervical Ripening Using Misoprostol vs Dinoprostone: A randomised, triple-blinded, interventional study comparing safety and efficacy in primiparous women ACTRN12616000522415 John Hunter Hospital; Lookout Rd; New Lambton Heights; NSW 2305
Dr Angela Boulton
Angela.Boulton@hnehealth.nsw.gov.au		 Currently recruiting Labour, induction methods, cervical ripening Pregnant women
A randomised trial of a nasal barrier dressing to reduce nasal trauma in very preterm infants receiving continuous positive airway pressure (CPAP) or nasal intermittent positive pressure ventilation (NIPPV) treatment: The ProNose study 00-9908977654321`234567--=\\\][POU A randomised trial of a nasal barrier dressing to reduce nasal trauma in very preterm infants receiving continuous positive airway pressure (CPAP) or nasal intermittent positive pressure ventilation (NIPPV) treatment: The ProNose study;. Currently recruiting
ProNose study - A randomised trial of a nasal barrier dressing to reduce nasal trauma in very preterm infants receiving continuous positive airway pressure (CPAP) or nasal intermittent positive pressure ventilation (NIPPV) treatment ACTRN12616000438459 The Royal Women's Hospital ; Level 7, 20 Flemington Road; Parkville, VIC 3052; Australia
Dr Brett Manley
brett.manley@thewomens.org.au		 Currently recruiting Newborn, respiratory, preterm, nasal trauma Preterm newborns
EVARO study (Enteral vitamin A to improve Respiratory Outcomes) Oral vitamin A for prevention of bronchopulmonary dysplasia in extremely preterm infants: a randomised controlled trial ACTRN12616000408482 Department of Neonatal Paediatrics, King Edward Memorial Hospital, Subiaco, WA 6008
Dr Abhijeet Rakshasbhuvankar
abhijeet.rakshasbhuvankar@health.wa.gov.au		 Currently recruiting Newborn respiratory, extremely preterm, chronic lung disease prevention Extremely preterm newborns
PROTECT - Can Pentoxifylline improve long-term outcomes in preterm infants with late-onset sepsis or necrotizing enterocolitis? A pragmatic, randomized, controlled trial ACTRN12616000405415 NHMRC Clinical Trial Centre, NSW
protect@ctc.usyd.edu.au

 Currently recruiting
IMPACT reviewed
 Preterm infant sepsis and inflammation, neurodevelopment Born at less than 29 weeks gestational age with suspected late-onset sepsis or necrotizing enterocolitis
Evaluation of the C2u Project - Evaluation of the effectiveness of an infant and family health and wellbeing text message intervention (Connecting 2u) in supporting expectant and new parents ACTRN12616000072415 Children's Health Queensland, South Brisbane, QLD 4101
Ms Cindy Dawson
Cindy.Dawson@health.qld.gov.au		 Currently recruiting Parenting support Pregnant women