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Trial Name Trial ID Main Coordinating Centre
and contact		 Status Recruitment Topic Participants Details
Foley Catheter Latex versus Silicone for Cervical Ripening Prior to Term Induction of Labour: a randomized controlled trial ACTRN12615000795594 Westmead Hospital; Dr Terry McGee, Terry.McGee@health.nsw.gov.au Currently recruiting Latex; Silicon; Foley catheter This is a prospective randomized clinical trial that is carried out in the Day Assessment Unit and the Birth Unit (the usual sites of Foley catheter insertion) at Westmead Hospital . All women 16 years and over booked for cervical ripening with a Foley catheter before term induction of labour are asked to participate in the study.
Apart from the randomization of catheter material (latex v silicone) all other care will be identical to women not participating in the study.
To2rpido Study - Targeted Oxygenation in the Resuscitation of Premature Infants and their Developmental Outcome. (formally recorded as) Feasibility of Multinational Trial of Targeted Oxygen for the Resuscitation of Premature Infants and their Development ACTRN12610001059055 Dept of Newborn Care, Royal Hospital for Women, NSW ju.oei@sesiahs.health.nsw.gov.au Currently recruiting Newborn resuscitation
Ultrasound in the second stage of labour for fetal position ? a randomised controlled trial ACTRN12615001213538 Dept of Obstetrics & Gynaecology, Ipswich Hospital kassam_mahomed@health.qld.gov.au Currently recruiting
COPRA - A pilot randomised controlled trial of outpatient balloon catheter priming for induction of labour ACTRN12612001184864 Women`s & Children`s Hospital chrisswilkinson@mac.com Currently recruiting Pregnancy is at term (37 completed weeks to 42 completed weeks), intact membranes, induction being performed for post-dates or social reason, singleton, appropriately grown by clinical exam, cephalic presentation. (Clinical suspicion of growth restriction investigated by ultrasound assessment). -Cervical ripening for reasons other than fetal or maternal compromise.
ORIP - Omega-3 fats to reduce the incidence of prematurity ACTRN12613001142729 Women`s and Children`s Health Research Institute, SA (WCH) jo.zhou@adelaide.edu.au Currently recruiting Preterm birth ? prevention and treatment. Maternal nutrition Women at less than 20 weeks' gestation
GRoW - Metformin and dietary advice to improve insulin sensitivity and promote gestational restriction of weight in pregnant women who are obese - a randomised trial ACTRN12612001277831 Discipline of Obstetrics & Gynaecology, The University of Adelaide andrea.deussen@adelaide.edu.au Currently recruiting Obesity. Maternal nutrition Women with a singleton, live gestation between 10 +0 and 20 +0 weeks gestation with a BMI above or equal to 30 kg/m2 at their first antenatal visit.
BUGS Trial - Randomized Double-blind Placebo-controlled Trial of Probiotics in Pregnancy and its effect on Group-B Streptococcal Colonization ACTRN12615000239561 Fiona Stanley Hospital WA shailender.mehta@health.wa.gov.au Currently recruiting
A RCT of pregnant women being monitored during labour with ST analysis monitoring and cardiotocography compared to being monitored with cardiotocography alone in order to reduce caesarean section whilst still having comparable outcomes for the baby. ACTRN12615001308583 Women's & Children's Hospital, Adelaide chrisswilkinson@mac.com Currently recruiting Labour and intrapartum care Women >= 18 years, gestation >36 completed weeks, expected to labour and deliver vaginally, singleton fetus, cephalic presentation, suitable for STan monitoring.
WASH*T - Effect of transfusion of washed red blood cells on neonatal outcome: a randomised controlled trial ACTRN12613000237785 Women's & Children's Hospital, SA michael.stark@adelaide.edu.au Currently recruiting Transfusion, Immunology and Neonatal Outcomes Infants born with a gestational age up to 28 weeks 6 days clinically requiring a packed red blood cell transfusion transfusion.
Propofol compared to morphine and midazolam for facilitating neonatal intubation: A randomized controlled trial ACTRN12608000277347 Grantley Stable Neonatal Unit, Royal Brisbane and Womens' Hospital, Brisbane Pieter_Koorts@health.qld.gov.au Currently recruiting
PREMM - Preterm infant massage by the mother ACTRN12612000335897 Grantly Stable Neonatal Unit, Royal Brisbane & Women's Hospital Naoni_Ngenda@health.qld.gov.au; p.colditz@uq.edu.au Currently recruiting
BELIEF - Birth Emotions looking to improve Expectant or Extreme Fear ACTRN12612000526875 Griffith University j.toohill@griffith.edu.au Currently recruiting
GluT pilot - Glucose Targets in gestational diabetes Pilot ACTRN12614001250628 Women's and Children's Hospital bill.hague@adelaide.edu.au Currently recruiting Diabetes. Maternal medical conditions Pregnant women with gestational diabetes diagnosed on 75g OGTT: fasting glucose >=5.5 mmol/L and 2h glucose >=8.5 mmol/L, between 12 and 30 weeks gestation, with a singleton or twin pregnancy, not previously diagnosed as diabetic
OptiMum - Optimising Protection for Pregnant Women with Influenza Vaccination ACTRN12614000374662 Women's and Children's Hospital Foundation helen.marshall@adelaide.edu.au Currently recruiting Pregnant women aged 18 to 40 years (inclusive) at the time of the vaccination
DIAMOND - DIfferent Approaches to MOderate & later preterm Nutrition: Determinants of feed tolerance, body composition and development ACTRN12616001199404 Liggins Institute, University of Auckland
t.alexander@auckland.ac.nz		 Currently recruiting
IMPACT endorsed
 Newborn nutrition Newborn body composition Neurodevelopment Preterm babies between 32+0 - 35+6 admitted to the neonatal unit requiring IV insertion
Premi Remi - A randomised double-blind placebo-controlled trial of the efficacy of Remifentanil for procedural pain in neonates ACTRN12612000385842 John Hunter Children's Hospital, NSW Ian.Wright@hnehealth.nsw.gov.au Currently recruiting
TASTE - Effect of smell and taste to improve nutrition in very preterm babies ACTRN12617000583347 Neonatal Critical Care Unit, Mater Mothers' Hospital, QLD 4101
Dr Friederike Beker
friederike.beker@mater.org.au		 Currently recruiting Newborn, nutrition, preterm, tube feeding Very preterm newborns
A micronutrient intervention for pregnant women experiencing symptoms of depression and anxiety ACTRN12617000354381 Mental Health and Nutrition Research Group, Department of Psychology, University of Canterbury, Christchurch 8140
Prof Julia Rucklidge
julia.rucklidge@canterbury.ac.nz		 Currently recruiting Maternal mental health, micronutrients Pregnant women
Determination of equivalent doses (ED50) of metaraminol and phenulephrine needed to prevent hypotension during elective caesarean section under regional anaesthesia King Edward Memorial Hospital for Women (KEMH) nolan.mcdonnell@health.wa.gov.au Currently recruiting Labour and intrapartum care
NIPA Trial (Nifedipine for improving Implantation and Pregnancy rates in ART) Does nifedipine improve implantation and pregnancy rates in women undergoing in-vitro fertilisation (IVF)/intracytoplasmic sperm injection (ICSI) cycles? ACTRN12617000213347 Melbourne IVF, East Melbourne, VIC, 3002
Dr Alex Polyakov
alex.polyakov@mivf.com.au		 Currently recruiting Reproductive medicine, IVF implantation, nifedipine Women
Efficacy of the Eating4Two smartphone application for the prevention of excessive gestational weight gain ACTRN12617000169347 University of Canberra, Bruce ACT, 2601
Prof Deborah Davis
deborah.davis@canberra.edu.au		 Currently recruiting Pregnancy, maternal weight gain, smart phone application Pregnant women
STREAM - Effect of ovarian stimulation on oocyte quality and embryonic aneuploidy: a prospective, randomised controlled trial ACTRN12616001539426 School of Women’s &amp, Children’s Health, Royal Hospital for Women, NSW 2031
Prof William Ledger
w.ledger@unsw.edu.au		 Currently recruiting Reproductive medicine, IVF, ovarian stimulation Women undergoing fertility treatment
SEETAP Trial - Evaluation of needle visibility during insertion of ultrasound guided transversus abdominis plane (TAP) blocks for women undergoing lower abdominal surgery ACTRN12612000549820 King Edward Memorial Hospital for Women, WA melanie_bloor@hotmail.com Currently recruiting Labour and intrapartum care
EPAR study - Early PARacetamol (EPAR) to promote early closure of the ductus arteriosus in preterm infants ACTRN12616001517460 Department of Newborn Care, Royal Hospital for Women, Barker St, Randwick NSW 2031
Dr Timothy Schindler
tschindl@med.usyd.edu.au		 Currently recruiting Newborn, preterm, ductus arteriosus Preterm newborns
SEED (Sleep, Eat, Emotions, and Development): Enhancing sleep and wellbeing in mothers and infants ACTRN12616001462471 Monash Institute of Cognitive and Clinical Neurosciences, Sleep Program, School of Psychological Sciences, Monash University, Clayton VIC 3800
Dr Bei Bei
bei.bei@monash.edu		 Currently recruiting Maternal and infant wellbeing, sleep Pregnant women
Integrated e-Screening for Postnatal Depression and Anxiety ACTRN12616001217493 Parent-Infant Research Institute, Heidelberg Repatriation Hospital, VIC 3081
Prof Jeannette Milgrom
jeannette.milgrom@austin.org.au		 Currently recruiting Maternal mental health, postnatal depression screening Pregnant women
SiMPro Study - Effect of single versus multi-strain probiotic supplementation on the time to full enteral feeds in preterm neonates ? a double blind randomised controlled trial ACTRN12615000940572 King Edward Memorial Hospital, WA gayatri.jape@health.wa.gov.au Currently recruiting
CRUMD - Cervical Ripening Using Misoprostol vs Dinoprostone: A randomised, triple-blinded, interventional study comparing safety and efficacy in primiparous women ACTRN12616000522415 John Hunter Hospital; Lookout Rd; New Lambton Heights; NSW 2305
Dr Angela Boulton
Angela.Boulton@hnehealth.nsw.gov.au		 Currently recruiting Labour, induction methods, cervical ripening Pregnant women
hPOD - Hypoglycaemia prevention in newborns with oral dextrose ACTRN12614001263684 Distinguished Prof Jane Harding, Principal Investigator, Liggins Institute, University of Auckland, Private Bag 92019, Auckland 1142, +6493737599 ext 86439, j.harding@auckland.ac.nz

Kelly Fredell, Clinical Research Coordinator, Research Development Coordinator,
Liggins Institute, University of Auckland, Private Bag 92019, Auckland 1142,
+64 9 923 7720 Ext 87720, k.fredell@auckland.ac.nz		 Currently recruiting In newborn infants at risk of hypoglycaemia does prophylactic oral dextrose gel compared to placebo reduce admission to Newborn Intensive Care Unit (NICU) Newborn babies at risk of hypoglycaemia
A randomised trial of a nasal barrier dressing to reduce nasal trauma in very preterm infants receiving continuous positive airway pressure (CPAP) or nasal intermittent positive pressure ventilation (NIPPV) treatment: The ProNose study 00-9908977654321`234567--=\\\][POU A randomised trial of a nasal barrier dressing to reduce nasal trauma in very preterm infants receiving continuous positive airway pressure (CPAP) or nasal intermittent positive pressure ventilation (NIPPV) treatment: The ProNose study;. Currently recruiting
ProNose study - A randomised trial of a nasal barrier dressing to reduce nasal trauma in very preterm infants receiving continuous positive airway pressure (CPAP) or nasal intermittent positive pressure ventilation (NIPPV) treatment ACTRN12616000438459 The Royal Women's Hospital ; Level 7, 20 Flemington Road; Parkville, VIC 3052; Australia
Dr Brett Manley
brett.manley@thewomens.org.au		 Currently recruiting Newborn, respiratory, preterm, nasal trauma Preterm newborns
A cluster randomised trial to evaluate the effectiveness of a telephone based coaching program in reducing excessive gestational weight gain amongst pregnant women - pilot ACTRN12615000397516 Liverpool Hospital
michelle.maxwell@sswahs.nsw.gov.au		 Currently recruiting
EVARO study (Enteral vitamin A to improve Respiratory Outcomes) Oral vitamin A for prevention of bronchopulmonary dysplasia in extremely preterm infants: a randomised controlled trial ACTRN12616000408482 Department of Neonatal Paediatrics, King Edward Memorial Hospital, Subiaco, WA 6008
Dr Abhijeet Rakshasbhuvankar
abhijeet.rakshasbhuvankar@health.wa.gov.au		 Currently recruiting Newborn respiratory, extremely preterm, chronic lung disease prevention Extremely preterm newborns
PROTECT - Can Pentoxifylline improve long-term outcomes in preterm infants with late-onset sepsis or necrotizing enterocolitis? A pragmatic, randomized, controlled trial ACTRN12616000405415 NHMRC Clinical Trial Centre, NSW
protect@ctc.usyd.edu.au

 Currently recruiting
IMPACT reviewed
 Preterm infant sepsis and inflammation, neurodevelopment Born at less than 29 weeks gestational age with suspected late-onset sepsis or necrotizing enterocolitis
PROTECTIVE - A study to assess whether two different doses of antenatal intravenous iron administration (500 mg and 1000mg ferric carboxymaltose) are equivalent in replenishing and sustaining iron stores successfully in pregnant iron deficient women ACTRN12615000950561 Lyell McEwin Hospital, A/Prof Bernd Froessler Currently recruiting IV iron in pregnancy and post-partum Pregnant and post partum women
ICARIS - Impact of Caesarean Rates following Injections of Sterile Water: a randomised controlled trial ACTRN12611000221954 Mater Health Services nigel.lee@mater.org.au Currently recruiting Labour and intrapartum care
Evaluation of the C2u Project - Evaluation of the effectiveness of an infant and family health and wellbeing text message intervention (Connecting 2u) in supporting expectant and new parents ACTRN12616000072415 Children's Health Queensland, South Brisbane, QLD 4101
Ms Cindy Dawson
Cindy.Dawson@health.qld.gov.au		 Currently recruiting Parenting support Pregnant women
STOP Trial - Supporting Threatened Outcomes with Progesterone In women with threatened miscarriage, does progesterone supplementation increase the likelihood of live birth? ACTRN126110000405910 Mater Mothers' Hospital naturalfertility@mater.org.au Currently recruiting
ACCORd - Efficacy of training general practitioners in structured contraceptive counselling for increasing use of long-acting reversible contraception (LARC): The Australian Contraceptive ChOice pRoject ACTRN12615001346561 Department of General Practice, School of Primary Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University, Building 1, 270 Ferntree Gully Road, Notting Hill, Victoria 3168
Prof Danielle Mazza, danielle.mazza@monash.edu		 Currently recruiting
OACC - Effect of timing of oxytocin administration during delayed cord clamping in term infants ACTRN12615001299594 The Ritchie Centre, Level 5, Monash Medical Centre, 246 Clayton Road, Clayton, VIC 3168
Prof Euan M Wallace, euan.wallace@monash.edu		 Currently recruiting
Intrauterine local anaesthetic after hysteroscopy to reduce post operative pain - A Randomised controlled trial ACTRN12615001214527 Dept of Obstetrics and Gynaecology, Ipswich Hospital, 1 Chelmsford Avenue, Ipswich, Qld 4305
A/Prof Kassam Mahomed, kassam_mahomed@health.qld.gov.au		 Currently recruiting
PINC BALLOON Study - Prostaglandin Inpatient Induction of labour Compared with BALLOon Outpatient iNduction of labour: a randomised controlled trial ACTRN12614000039684 Mater Mother's Hospital, South Brisbane, Queensland Australia. Dr Michael Beckmann (Chief Investigator) michael.beckmann@mater.org.au Currently recruiting Induction of labour, IOL, pregnancy All women with live singleton pregnancies >37 weeks booked for induction of labour for post-term, social or elective reasons and require cervical priming.
Improving primary care for Aboriginal mothers and babies in the Kimberley region of Western Australia ‘Nini Helthiwan’: a population and region based cluster randomised trial driven by local health service providers ACTRN12615001060538 The University of Western Australia, School of Paediatrics and Child Health (M561), 35 Stirling Highway Crawley WA 6009
Prof Karen Edmond, karen.edmond@uwa.edu.au		 Currently recruiting
The ABC Study - Assisted breathing before cord clamping ACTRN12615001026516 Neonatal Care, Middlemore Hospital, Private Bag 93311, Otahuhu, Auckland 1640
Mrs Elizabeth Nevill, elizabeth.nevill@cmdhb.org.nz		 Currently recruiting
PMTrial - In pregnant women with previous subfertility, does progesterone supplementation decrease the likelihood of miscarriage? ACTRN12611000401954 Mater Mothers` Hospital QLD naturalfertility@mater.org.au Currently recruiting
Hysteroscopic Morcellator versus Electrosurgical resection for Submucosal Leiomyoma ACTRN12615000828527 School of Women's and Children's Health, Level 1, Barker St, Randwick, NSW, 2031 Currently recruiting
The construction and experience of fertility in the context of cancer: Patient, partner and health professional perspectives ACTRN12615000624583 Centre for Health Research, School of Medicine University of Western Sydney, Locked Bag 1797, Penrith NSW 2751
Prof Jane Ussher, j.ussher@uws.edu.au		 Currently recruiting
Can artificial blastocoele shrinkage prior to vitrification improve the vitrification process, improve post-thaw survival and improve pregnancy outcomes ACTRN12615000453583 Fertility SA, St Andrews Hospital, 350 South Tce, Adelaide, South Australia, 5000
Mr Michael Barry, mbarry@fertilitysa.com.au		 Currently recruiting
SWAB study - Sexual Well Being After Breast cancer study ACTRN12615000083594 Women's Health Research Program Monash University Level 6, The Alfred, Centre 99 Commercial Rd, Melbourne, Victoria 3004
Prof Susan Davis, susan.davis@monash.edu		 Currently recruiting
LIFT - Lactoferrin Infant Feeding Trial to prevent sepsis and death in preterm infants ACTRN12611000247976 NHMRC Clinical Trial Centre, NSW

lift@ctc.usyd.edu.au		 Currently recruiting
IMPACT reviewed