TIPPS - Thrombophilia in pregnancy prophylaxis study: a multicentre, multinational, randomised controlled trial of prophylactic low molecular weight heparin in high-risk pregnant thrombophilic women |
ISRCTN87441504 |
The University of Ottawa Hospital, Ontario, Canada, Professor Marc Rodger (Chief Investigator). Suzette Coat - Australian Coordinator |
Recruitment complete
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Preeclampsia. Fetal growth |
Pregnant women with thrombophilia at increased risk of venous thromboembolism or with previous placenta mediated pregnancy complication prior to 20 weeks gestation |
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HATCh - The effects of antenatal hypnosis on pain relief in labour |
ACTRN12605000018617 / NCT00282204 |
Women's & Children's Hospital Allan Cyna |
Recruitment complete
|
Labour and intrapartum care |
Previous hypnosis for childbirth; woman definitely wants an epidurtal or hypnosis; Not singleton live fetus before 34 weeks gestation; Other conditions causing pain; Active psychiatric illness. |
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PPROMT - Immediate delivery vs expectant care in women with preterm prelabour rupture of the membranes close to term - A randomised clinical trial |
PT0536/ISRCTN44485060/NHMRC358378 |
Dept of Obstetrics & Gynaecology, Royal North Shore Hospital ppromt@med.usyd.edu.au |
Recruitment complete
|
Preterm birth ? improving outcomes (antenatal interventions) |
Singleton pregnancies, with confirmed ruptured membranes from 34 weeks to 36 weeks and 6 days gestation. |
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MILO - Oral misoprostol for the induction of labour at term |
PT0361/ACTRN012606000156583 |
Women's and Children's Hospital , SA jodie.dodd@adelaide.edu.au |
Recruitment complete
|
Labour and intrapartum care |
Singleton pregnancy, at a gestational age of 37 weeks or more, planned induction of labour for defined obstetric and medical conditions - prolonged pregnancy, pre-eclampsia, hypertensive disoreders, antepartum haemorrhage (ecluding placenta praevia), oligohydramnios, IUGR, or abnormal glucose tolerance. |
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A double-blind randomised controlled trial of oxytocin bolus plus placebo infusion versus oxytocin bolus plus oxytocin infusion at elective caesarean section |
ACTRN12607000631404 |
Monash Medical Centre joanne.mockler@med.monash.edu.au |
Discontinued
|
Labour and intrapartum care |
Singleton pregnancy, gestation 37 - 41 weeks, elective lower segment caesarean section, regional anaesthesia (spinal, epidural, combined spinal epidural (CSE)) |
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ACTORDS - Australasian Collaborative Trial of Repeat Doses of Corticosteroids for the Prevention of Neonatal Respiratory Disease |
ACTRN12606000318583; PT0349; ISRCTN48656428 |
Adelaide Women's and Children's
pat.ashwood@adelaide.edu.au |
Recruitment complete
|
Preterm birth improving outcomes (antenatal interventions). Newborn respiratory |
Singleton, twin or triplet pregnancy at less than 32 weeks gestation; 7 or more days since first corticosteroid treatment, remaining at risk of preterm delivery |
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Twin birth study (TBS): a multicentred randomised controlled trial comparing planned caesarean section with planned vaginal birth for twins at 32-38 weeks gestation |
PT0540/ISRCTN74420086/ACTRN12606000267550 |
University of Toronto Dalah Mason |
Recruitment complete
|
Labour and intrapartum care |
Twins where twin A is cephalic, gestational age 32-38 weeks, estimated fetal weight 1500-4000g, both twins alive. |
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Oral misoprostol versus intravenous oxytocin for induction of labour following artificial or spontaneous rupture of membranes |
|
jodie.dodd@adelaide.edu.au |
Recruitment complete
|
Labour and intrapartum care |
Women > or = 41 weeks booked for delivery at Women's and Children's Hospital; singleton pregnancy; cephalic presentation |
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The influence of acupuncture on the induction of labour for women with a post date pregnancy: a randomised controlled trial. |
PT0348 / ACTRN12606000494538 |
caroline.smith@uws.edu.au |
Recruitment complete
|
Labour and intrapartum care |
Women > or = 41 weeks; singleton pregnancy; cephalic presentation |
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HUGS - Early intervention to protect the mother-infant relationship following postnatal depression - a randomised controlled trial |
ACTRN12612001110875 |
Parent-Infant Research Institute, Austin Health, (03) 9496 4496, piri@austin.org.au
|
Recruitment complete
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Postnatal depression, mother-infant interaction |
Women aged 18 years or older with an infant aged 3-9 months and a clinical diagnosis of current major or minor depressive episode |
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USES Trial - Women's Opinions and Experiences of Prenatal Screening for Down Syndrome |
PT0355 |
caroline.crowther@adelaide.edu.au |
Recruitment complete
|
Fetal surveillance. Fetal anomaly |
Women at less than 14 weeks gestation who have not had a dating scan or nuchal translucency screening |
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IRIS - A randomised clinical trial of different infusion rates of magnesium sulphate given prenatally to women for the prevention of side effects |
ACTRN12605000765628 |
Women's and Children's Hospital, SA caroline.crowther@adelaide.edu.au |
Recruitment complete
|
Preterm birth ? improving outcomes (antenatal interventions) |
Women at less than 30 weeks gestation where birth is planned or definitely expected within 24 hours. |
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A*STEROID - Australasian Antenatal Study to Evaluate the Role Of Intramuscular Dexamethasone versus betamethasone prior to preterm birth to increase survival free of childhood neurosensory disability - a randomised controlled trial |
ACTRN12608000631303 |
The University of Adelaide / Women's & Children's Hospital pat.ashwood@adelaide.edu.au |
Recruitment complete
|
Preterm birth ? improving outcomes (antenatal interventions). Newborn respiratory |
Women at risk of preterm birth at less than 34 weeks gestation, have a singleton or twin pregnancy and no contraindications to the use of antenatal corticosteroids |
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IDEAL - Dietary and Lifestyle advice for women with borderline gestational glucose intolerance |
ACTRN12607000174482 |
Australian Research Centre for Health of Women and Babies (ARCH), The University of Adelaide pat.ashwood@adelaide.edu.au |
Recruitment complete
|
Diabetes. Maternal nutrition |
Women between 24 weeks 0 days and 34 weeks 6 days gestation with a singleton pregnancy, with a positive OGCT (venous plasma glucose >=7.8 mmol/L) and a normal 75 gram OGTT (fasting venous plasma glucose <5.5 mmol/L and a 2 hour glucose <7.8 mmol/L), |
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CLOSURE - Skin and subcutaneous fascia closure at caesarean section: a randomised controlled trial |
ACTRN12608000143325 |
Discipline of Obstetrics and Gynaecology, Women's and Children's Hospital rosalie.grivell@adelaide.edu.au |
Recruitment complete
|
Labour and intrapartum care |
Women undergoing a caesarean section by transverse suprapubic incision |
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MPG Trial - Metformin in the Prevention of Gestational Diabetes |
ACTRN12610000157077 |
Women`s and Children`s Hospital, Children`s Youth and Women`s Health Service, North Adelaide suzette.coat@adelaide.edu.au |
Discontinued
|
Prevention of recurrent Gestational diabetes |
Women who have had a previous pregnancy affected by GDM |
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Help-seeking for postnatal depression as a major public health problem: A cluster randomised controlled trial of motivational interviewing |
ACTRN12611000635965 |
Parent-Infant Research Institute, Austin Health, (03) 9496 4496, piri@austin.org.au
|
Recruitment complete
|
Motivational interviewing, postnatal depression |
Women with a 4-week old baby |
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BAC - Birth after Caesarean. Planned vaginal birth or planned caesarean section for women at term with a single previous caesarean birth |
ISRCTN53974531/NHMRC349460 |
Maternal Perinatal Clinical Trials Unit, Adelaide Women's and Children's
Pat Ashwood |
Recruitment complete
|
Labour and intrapartum care |
Women with a single prior caesarean presenting in their next pregnancy with a single live fetus in cephalic presentation who have reached 37 weeks gestation, and who don't have a contraindication to a planned VBAC. |
|
Improving oral hygiene to reduce the risk of preterm birth: A randomised controlled trial assessing a high intensity educational intervention |
ACTRN12605000767606 |
caroline.crowther@adelaide.edu.au |
Discontinued
|
Preterm birth ? prevention and treatment |
Women with a singleton pregnancy |
|
ACTOTTAB - Twins: Timing of birth at Term |
PT0426/ISRCTN15761056 |
WCH, Adelaide Jodie Dodd |
Recruitment complete
|
Labour and intrapartum care. Models of care |
Women with a twin pregnancy at 37 weeks gestation |
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DIAMIND - Diabetes SMS text reminders versus standard care for women who have had gestational diabetes mellitus to increase the rate of oral glucose testing in the postpartum period |
ACTRN12612000621819 |
Australian Research Centre for Health of Women & Babies, The University of Adelaide emer.heatley@adelaide.edu.au |
Recruitment complete
|
Diabetes. Maternal medical conditions |
Women with GDM in current pregnancy, singleton or twin pregnancy, with access to a mobile phone, postnatal blood glucose that level returned to normal before discharge |
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STRIDER (NZAus)- A randomised placebo-controlled trial of a new therapy (sildenafil) to help growth in severely growth restricted fetuses at very early gestations |
ACTRN12612000584831 |
Department of Obstetrics and Gynaecology, University of Auckland Laura Mackay (Trial Manager) laura.mackay@auckland.ac.nz; Dr Katie Groom (Chief Investigator) k.groom@auckland.ac.nz |
Recruitment complete
IMPACT reviewed
|
Fetal growth. Preeclampsia. Pterterm birth - prevention and treatment |
Women with pregnancies complicated early onset fetal growth restriction. Abdominal circumference ≤3rd centile at 22-28 weeks or EFW <700g at 28-80 weeks |
View |
PLUTO - Percutaneous shunting for lower urinary tract obstruction |
ISRCTN53328556 |
The Clinical Trials Unit, University of Birmingham. Professor Mark Kilby (Chief Investigator) m.d.kilby@bham.ac.uk |
Recruitment complete
|
Fetal anomaly |
women with pregnancy with a male fetus complicated by isolated lower urinary tract obstruction (LUTO) |
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EPPI Trial - Enoxaparin for the Prevention of Preeclampsia and Intrauterine growth restriction ? a pilot randomised placebo-controlled trial |
ACTRN12609000699268 |
Department of Obstetrics and Gynaecology, University of Auckland. Laura Mackay (Trial Manager) laura.mackay@auckland.ac.nz; Dr Katie Groom (Chief Investigator) k.groom@auckland.ac.nz |
Recruitment complete
IMPACT reviewed
|
Fetal growth. Preeclampsia |
Women with previous pregnancy complicated by early onset preeclampsia or fetal growth restriction |
View |
FRUIT-Study - Low-molecular-weight heparin added to aspirin in the prevention of recurrent early-onset pre-eclampsia in women with inheritable thrombophilia |
ISRCTN87325378 |
Department of Obstetrics and Gynaecology, VU University Medical Center, Amsterdam,
Netherlands.
Prof JIP de Vries (Chief Investigator) jip.devries@vumc.nl |
Recruitment complete
|
Preeclampsia. Fetal growth. Maternal medical conditions |
women with previous pregnancy with hypertensive disease and/or SGA <34 weeks and an inheritable thrombophilia
|
|
HEPRIN - Heparin for the Prevention of complications related to placental Insufficiency |
ISRCTN88675588 |
Mt Sinai Hospital, Professor Jodie Dodd (Principal Investigator) jodie.dodd@adelaide.edu.u |
Recruitment complete
|
Preeclampsia. Fetal growth |
Women with significant risk factors for placental insufficiency (low PAPP-A, high AFP, high inhibin, high hCG, medical and obstetric risk factors or abdnormal uterine artery Doppler) |
|
NIFTY - A multi-centre randomised double blind placebo controlled trial of nifedipine maintenance tocolysis in fetal fibronectin positive women in threatened preterm labour |
ACTRN12613000985785 |
National Women's Health, Auckland Hospital. Dr Emma Parry (Principal Investigator) EmmaP@adhb.govt.nz |
Recruitment complete
|
Preterm birth ? prevention and treatment |
Women with threatened preterm labour, a singleton pregnancy, gestational age between 24 and 34 weeks, intact membranes, positive fetal fibronectin test, completed course of corticosteroids |
|
Open versus specific questioning to assess pain during anaesthetic follow-up after caesarean birth: a randomised trial |
ACTRN12609000121268 |
Women's & Children's Hospital Allan Cyna |
Recruitment complete
|
Labour and intrapartum care |
Women within 72 hour of their caesarean section |
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