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Trial Name Trial ID Main Coordinating Centre
and contact		 Status Recruitment Topic Participants Details
ACTOTTAB - Twins: Timing of birth at Term PT0426/ISRCTN15761056 WCH, Adelaide Jodie Dodd Recruitment complete Labour and intrapartum care. Models of care Women with a twin pregnancy at 37 weeks gestation
Pain versus comfort scores after caesarean section: a randomised trial ACTRN12610000890033 Department of Women's Anaesthesia, Women's & Children's Hospital Allan Cyna Recruitment complete Labour and intrapartum care All English speaking women who are scheduled for post-anaesthesia review following caesarean section.
BOOST II: Benefits Of Oxygen Saturation Target BOOST II. Which oxygen saturation level should we use for very premature infants? A randomised controlled trial to investigate the effect of two slightly different oxygen levels on the health of very premature infants ACTRN12605000055606/NHMRC352386 Westmead Children's, NSW Alpana Ghadge Recruitment complete
MEAN ITCH Trial - Does methylnaltrexone reduce the incidence and severity of itch following spinal anaesthesia with intrathecal morphine in women undergoing caesarean delivery ACTRN12612000572864 Dept of Anaesthesia & Pain Medicine,<br>King Edward Memorial Hospital for Women michael.paech@health.wa.gov.au Recruitment complete Labour and intrapartum care
Does Vitamin D supplementation in pregnancy improve maternal glucose metabolism or prevent gestational diabetes? ACTRN12612001145897 Westmead Hospital m.mclean@uws.edu.au Recruitment complete
Does the use of a patient information video affect maternal antenatal anxiety and post-natal maternal satisfaction after elective caesarean delivery? ACTRN12611001207909 Dept of Anaesthesia, Royal Brisbane and Women's Hospital victoria_eley@health.qld.gov.au Recruitment complete
Probiotic Eczema Prevention Study (CSG Trial No. 36) Dept of Immunology, Royal Children's Hospital, Vic Robert Boyle Recruitment complete
Healthy Living Program after Gestational Diabetes ACTRN12614000539639 Westmead Hospital wah.cheung@sydney.edu.au Recruitment complete
INIS - International Neonatal Immunotherapy Study ACTRN012606000273583; NHMRC301973; PTO373 Westmead Hospital, NSW Priya Duggal-Beri Recruitment complete Newborn infection
PPROMT - Immediate delivery vs expectant care in women with preterm prelabour rupture of the membranes close to term - A randomised clinical trial PT0536/ISRCTN44485060/NHMRC358378 Dept of Obstetrics & Gynaecology, Royal North Shore Hospital ppromt@med.usyd.edu.au Recruitment complete Preterm birth ? improving outcomes (antenatal interventions) Singleton pregnancies, with confirmed ruptured membranes from 34 weeks to 36 weeks and 6 days gestation.
MPG Trial - Metformin in the Prevention of Gestational Diabetes ACTRN12610000157077 Women`s and Children`s Hospital, Children`s Youth and Women`s Health Service, North Adelaide suzette.coat@adelaide.edu.au Discontinued Prevention of recurrent Gestational diabetes Women who have had a previous pregnancy affected by GDM
N3RO - Can omega 3 fatty acids improve respiratory outcomes in preterm infants? ACTRN12612000503820 Women's & Children's Health Research Institute carmel.collins@health.sa.gov.au Recruitment complete
IMPACT reviewed
 Newborn respiratory Born at less than 29 weeks gestational age, within 3 days of commencing enteral feeds
CLOSURE - Skin and subcutaneous fascia closure at caesarean section: a randomised controlled trial ACTRN12608000143325 Discipline of Obstetrics and Gynaecology, Women's and Children's Hospital rosalie.grivell@adelaide.edu.au Recruitment complete Labour and intrapartum care Women undergoing a caesarean section by transverse suprapubic incision
POPPET - Providing Optimal Protein for Prems via Enteral Tubes. Does increasing the protein content of human milk fortifier improve growth in preterm infants <33 weeks gestation? A randomised controlled trial. ACTRN12611001275954 Women's & Children's Health Research Institute jessica.reid@adelaide.edu.au Recruitment complete Newborn nutrition Infants <33 completed weeks gestation whose mothers intend to provide breast milk
Effect of maternal egg consumption on breast milk ovalbumin concentration Women's & Children's Hospital Recruitment complete Maternal nutrition
A comparison of fentanyl with pethidine for pain relief during childbirth ACTRN126090001027202 Flinders University/Flinders Medical Centre
Julie Fleet		 Recruitment complete Labour and intrapartum care
HATCh - The effects of antenatal hypnosis on pain relief in labour ACTRN12605000018617 / NCT00282204 Women's & Children's Hospital Allan Cyna Recruitment complete Labour and intrapartum care Previous hypnosis for childbirth; woman definitely wants an epidurtal or hypnosis; Not singleton live fetus before 34 weeks gestation; Other conditions causing pain; Active psychiatric illness.
The effects of health related bio-markers in healthy women of child-bearing age consuming a diet higher in fish when compared to those who consumed a typical Australian diet higher in meat ACTRN12610000572066 Flinders Univesity lily.chan@flinders.edu.au Recruitment complete
Open versus specific questioning to assess pain during anaesthetic follow-up after caesarean birth: a randomised trial ACTRN12609000121268 Women's & Children's Hospital Allan Cyna Recruitment complete Labour and intrapartum care Women within 72 hour of their caesarean section
OSCAR - Women undergoing combined spinal epidural for elective caesarean section, ondansetron 8mg versus placebo to prevent perioperative shivering ACTRN12609000445279 Fremantle Hospital roger.browning@health.wa.gov.au Recruitment complete Labour and intrapartum care
Safety of supplementing infant formula with long-chain polyunsaturated fatty acids and Bifidobacterium lactis in term infants: a randomised controlled trial Women's & Children's Hospital, CYWHS Maria Makrides Recruitment complete Newborn nutrition
HINT Trial - High-flow nasal cannulae versus ambient oxygen for the treatment of newborn infants with early respiratory distress in non-tertiary special care nurseries: a multicentre, randomised controlled trial ACTRN12611000233921 Gosford Hospital and The Royal Women's, Melbourne abuckmaster@nsccahs.health.nsw.gov.au Discontinued Newborn respiratory
MILO - Oral misoprostol for the induction of labour at term PT0361/ACTRN012606000156583 Women's and Children's Hospital , SA jodie.dodd@adelaide.edu.au Recruitment complete Labour and intrapartum care Singleton pregnancy, at a gestational age of 37 weeks or more, planned induction of labour for defined obstetric and medical conditions - prolonged pregnancy, pre-eclampsia, hypertensive disoreders, antepartum haemorrhage (ecluding placenta praevia), oligohydramnios, IUGR, or abnormal glucose tolerance.
Hypnosis for nausea and vomiting in early pregnancy a randomised controlled trial ACTRN12607000127404 Women's and Children's Hospital Alan Cyna alan.cyna@adelaide.edu.au Recruitment complete Maternal medical conditions Pregnant women suffering from nausea and vomiting of pregnancy.
LIMIT - Limiting weight gain in overweight and obese women during pregnancy to improve health outcomes: a randomised trial ACTRN12607000161426 Women's and Children's Hospital Andrea Deussen Recruitment complete Obesity. Maternal nutrition Pregnant women with a singleton, live gestation between 10+0 - 20 weeks who are obese or overweight (defined as a body mass index greater that 25kg/m2)
DRESSING Trial - ADding negative pRESSure to improve healING in obese women undergoing caesarean section - PILOT ACTRN12612000171819 Griffith University w.chaboyer@griffith.edu.au Recruitment complete Labour and intrapartum care. Obesity
Toward Parenthood: delivering an antenatal self-help intervention with telephone support for depression, anxiety and parenting difficulties - facilitating the perinatal health journey ACTRN12606000263594 Heidelberg Repatriation Hospital, Vic Jennifer Ericksen Recruitment complete
OPRA - Outpatient cervical priming for induction of labour ACTRN12608000249358 Women's and Children's Hospital chrisswilkinson@mac.com Recruitment complete Models of care. Labour and intrapartum care Pregnant women having priming for induction of labour, where induction is clinically indicated, there is no evidence of maternal or fetal compromise and in the opinion of the referring caregiver, outpatient management and monitoring is clinically appropriate
MAP study - Managing asthma in Pregnancy ACTRN12607000561482 Hunter Hospital Recruitment complete
A randomised controlled trial of a brief multi strategic child health nurse intervention to reduce infant secondhand smoke exposure ACTRN12614001032640 Hunter New England Health justine.daly@hnehealth.nsw.gov.au Recruitment complete
DINO trial - Docosahexaenoic acid (DHA) for the improvement of neurodevelopmental outcome in preterm infants PT0424/NHMRC250322/ACTRN12606000327583 Women's and Children's Hospital Suzanne McCusker Recruitment complete Newborn nutrition. Newborn ? developmental Infants born < or = 32 weeks gestation
A randomised controlled trial comparing immediate and controlled release oxycodone the day after caesarean section ACTRN12613000076774 Ipswich Hospital, QLD Anthony_Schoenwald@health.qld.gov.au Recruitment complete
IRIS - A randomised clinical trial of different infusion rates of magnesium sulphate given prenatally to women for the prevention of side effects ACTRN12605000765628 Women's and Children's Hospital, SA caroline.crowther@adelaide.edu.au Recruitment complete Preterm birth ? improving outcomes (antenatal interventions) Women at less than 30 weeks gestation where birth is planned or definitely expected within 24 hours.
Bovine lactoferrin supplementation for prevention of necrotizing enterocolitis in very-low-birth-weight neonates: a randomized clinical trial ISRCTN53107700 Italy Michael Meyer Recruitment complete
Carbetocin vs oxytocin at emergency caesarean section ACTRN12612000466842 Women's Health Unit, Frankson Hospital, Vic Prof Amar Trivedi Recruitment complete Labour and intrapartum care
HeLP for Mums - A community based low intensity lifestyle intervention to prevent weight gain in women with children ACTRN12608000110381 Jean Hailes Foundation for Women Health/ Monash University catherine.lombard@monash.edu Recruitment complete
An early sleep psychoeducational intervention to improve sleep management and reduce depressive symptoms in new mothers ACTRN12611000859987 Woolcock Institute of Medical Research Liora.Kempler@sydney.edu.au Recruitment complete
HeLP-her - Healthier lifestyles: Preventing excess weight gain and gestational diabetes in overweight and obese pregnancies: a research and education project ACTRN12608000233325 Jean Hailes Research Group for Womens Health and Monash Institute of Health Services Research (Southern Health)MIMR Recruitment complete Obesity. Diabetes
A randomised controlled trial of dark chocolate in pregnancy for reduction in incidence of pre-eclampsia ISRCTN41164968 John James Medical Centre, Australian National University
stephen.robson@anu.edu.au		 Recruitment complete Preeclampsia
Balloon Trial - Caesarean section following induction of labour in nulliparous women with an unfavourable cervix: a comparison of three ripening agents - PGE2 Gel, single or double balloon catheter. ACTRN12609000186257 King Edward Memorial Hospital craig.pennell@uwa.edu.au Recruitment complete Labour and intrapartum care
CureNeb - Aerosolized surfactant in the first hour of life ACTRN12610000857000 King Edward Memorial Hospital Dr Stefan Minocchieri/Prof J J Pillow Discontinued Newborn respiratory
COMMAND Trial - Parecoxib, celecoxib and paracetamol for pain management following caesarean delivery. ACTRN12609001041246 King Edward Memorial Hospital for Women michael.paech@health.wa.gov.au Recruitment complete Labour and intrapartum care
The use of acupressure wristbands to prevent nausea and vomiting in labour and delivery ACTRN12607000585426 King Edward Memorial Hospital for Women, Perth Michael Paech Recruitment complete Labour and intrapartum care
Efficacy and safety of a new fish oil based lipid emulsion (SMOFlipid) compared with olive oil based lipid emulsion (Clinoleic) in preterm (<30 weeks) neonates - a randomised controlled trial ACTRN12609001017213 King Edward Memorial Hospital for Women, WA drgirishdeshpande@gmail.com Recruitment complete
SMOOTH - Oral analgesia compared with intrathecal morphine for pain after caesarean delivery: a randomised controlled trial ACTRN12606000506594 King Edward Memorial Hospital Michael Paech Recruitment complete
A randomised clinical trial at the time of spinal anaesthesia for elective caesarean section to investigate the effect of equipotent phenylephrine and metaraminol infusions on neonatal outcome ACTRN12612000996864 King Edward Memorial Hospital michael.paech@health.wa.gov.au Recruitment complete
Comparison of the EpiSure Autodetect syringe with the Portex loss-of-resistance syringe: a randomised controlled trial ACTRN12609000041257 King Edward Memorial Hospital, WA Suspended
Optimisation of the management of placental delivery in second trimester pregnancy interruption NCT00120042 King Edward Memorial Hospital, WA Jan Dickinson Recruitment complete
A prospective randomised trial to study the effect of intravenous iron therapy versus the standard treatment with oral iron for women diagnosed with iron deficiency anaemia in pregnancy ACTRN12609000177257 Launceston General Hospital
joanne.bates@dhhs.tas.gov.au		 Recruitment complete Maternal nutrition At risk women - dark skinned, veiled, Anyone with vitamin D deficiency that has not commenced treatment prior to recruitment
pre-hPOD - Hypoglycaemia prevention in newborns with oral dextrose ACTRN12613000322730 Liggins Insitute, University of Auckland Dr Jo Hegarty: j.hegarty@auckland.ac.nz Recruitment complete