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Trial Name Trial ID Main Coordinating Centre
and contact		 Status Recruitment Topic Participants Details
ELVIS - A Randomised Controlled Trial Investigating the Influence of BCG (Bacillus Calmette-Gu NCT02444611 Mercy Hospital for Women, Heidelberg lianne.cox@rch.org.au Recruitment complete
FFF - The effect of regular weighing and dietary advice on maternal health and complications of pregnancy in overweight pregnant women: Facts, figures and feelings about weight gain in pregnancy ACTRN12611000881932 Mercy Hospital for Women, Heidelberg, Vic ashub@mercy.com.au Recruitment complete
FLIP - Flavour for Infants born Preterm. Taste and Smell to improve milk tolerance in preterm infants ACTRN12614000661673 Mercy Hospital for Women, Vic fbeker@web.de Recruitment complete
MAMMA -Multidisciplinary Approach to Management of Maternal Asthma ACTRN12612000681853 Mercy Hospital for Women<br>Monash University Johnson.George@monash.edu Recruitment complete Maternal medical conditions
A comparison of two nasal continuous positive airway pressure interfaces - a randomized crossover study Middlemore Hospital/Univ of Auckland NZ
mmeyer@middlemore.co.nz		 Recruitment complete
A pilot randomised controlled trial to determine the effect of a physiological (step) versus a standard action (slope) labour progress lines on the rate of spontaneous vaginal birth amongst low risk women in labour for the first time ACTRN12614000786695 Midwifery Research Unit, Mater Research Institute
nigel.lee@mater.org.au		 Recruitment complete
A randomised controlled trial on the effects of antenatal vitamin D supplementation to improve vitamin D levels in the maternal and cord blood at birth in vitamin D deficient pregnant women ACTRN12609000142235 Monash Medical Centre Recruitment complete Maternal nutrition
A double-blind randomised controlled trial of oxytocin bolus plus placebo infusion versus oxytocin bolus plus oxytocin infusion at elective caesarean section ACTRN12607000631404 Monash Medical Centre joanne.mockler@med.monash.edu.au Discontinued Labour and intrapartum care Singleton pregnancy, gestation 37 - 41 weeks, elective lower segment caesarean section, regional anaesthesia (spinal, epidural, combined spinal epidural (CSE))
The effects of mindfulness training on maternal stress, depressed mood and present moment awareness: A pilot randomised trial ACTRN12614000523606 Monash University jill.beattie@monash.edu Recruitment complete Mindfulness, Pregnancy, Randomised trial Low risk pregnancy in the second trimester at the start of the intervention; 18 years or older; able to read and speak English; having a planned hospital birth; and who commit to attending all eight sessions.
RUBY - Ringing Up about Breastfeeding: a randomised control trial exploring earlY telephone peer support for breastfeeding ACTRN12612001024831 Mother & Child Health Research, La Trobe University The Royal Women`s Hospital, Melbourne, Victoria fiona.mclardiehore@thewomens.org.au Recruitment complete Breastfeeding, Peer support 1152 primiparous women with healthy singleton infant born at term, and planning to breastfeed
DAME - Diabetes and antenatal milk expressing a randomised controlled trial ACTRN12611000217909 Mother & Child Health Research, La Trobe University d.foster@latrobe.edu.au Recruitment complete Diabetes
MOVE Study - Improving maternal and child health care for women experiencing violence: collaborative development, implementation and effectiveness of a good practice model ACTRN12609000424202 Mother & Child Health Research, La Trobe University r.walter@latrobe.edu.au Recruitment complete Family violence
MOSAIC - GP cluster randomised trial to reduce partner violence among pregnant women and women with pre-school children ACTRN12607000010493/NHMRC 280617 Mother and Child Health Research, Vic a.taft@latrobe.edu.au Recruitment complete
HEPRIN - Heparin for the Prevention of complications related to placental Insufficiency ISRCTN88675588 Mt Sinai Hospital, Professor Jodie Dodd (Principal Investigator) jodie.dodd@adelaide.edu.u Recruitment complete Preeclampsia. Fetal growth Women with significant risk factors for placental insufficiency (low PAPP-A, high AFP, high inhibin, high hCG, medical and obstetric risk factors or abdnormal uterine artery Doppler)
e-prem - Improving child and parent outcomes after preterm birth using a web-based early intervention program ACTRN12614000906651 Murdoch Childrens Research Institute karli.treyvaud@mcri.edu.au Discontinued
NIFTY - A multi-centre randomised double blind placebo controlled trial of nifedipine maintenance tocolysis in fetal fibronectin positive women in threatened preterm labour ACTRN12613000985785 National Women's Health, Auckland Hospital. Dr Emma Parry (Principal Investigator) EmmaP@adhb.govt.nz Recruitment complete Preterm birth ? prevention and treatment Women with threatened preterm labour, a singleton pregnancy, gestational age between 24 and 34 weeks, intact membranes, positive fetal fibronectin test, completed course of corticosteroids
Prediction of normal vaginal delivery PT0547 Nepean Hospital Hans Peter Dietz Discontinued
Epi-No Trial: Effect of intravaginal balloon device on levator trauma in mothers following childbirth ACTRN12609000592246 Nepean Hospital, NSW hans.dietz@sydney.edu.au Recruitment complete
Sugar Babies Study Sugar Babies ACTRN12608000623392 Newborn Intensive Care, Waikato Hospital, Hamilton Dr Deborah Harrris: deborah.harris@waikatodhb.health.nz Recruitment complete
MONT (mask or nasal tube) Trial: A randomised controlled trial of mask versus nasal tube for the stabilisation of preterm infants (born between 24 and 29 complete weeks gestation) in the delivery room ACTRN12610000230055; NTR2061 Newborn Services and Neonatal Research, Royal Women's Hospital Omar Kamlin Recruitment complete Newborn resuscitation
APTS - Australian Placental Transfusion Study NHMRC571309; ACTRN12610000633088 NHMRC Clinical Trials Centre, The University of Sydney, NSW apts@ctc.usyd.edu.au Recruitment complete
AcuAnteDep - A pragmatic randomised controlled trial evaluating acupuncture as an antenatal intervention for the treatment of antenatal depression ACTRN12615000250538 NICM, Western Sydney University, caroline.smith@uws.edu.au Recruitment complete Antenatal depression, acupuncture, treatment Depressed pregnant women scoring 13 or more on the EDS at 24 weeks gestation
Folic Acid Clinic Trial (FACT) - Effect of folic acid supplementation in pregnancy on pre-eclampsia ISRCTN23781770; NCT01355159 Ottawa Health Research Institute, Ottawa, Canada bill.hague@adelaide.edu.au Recruitment complete Preeclampsia
BBBi - Beating the Blues before Birth (individual treatment) ACTRN12609000926235 Parent-Infant Research Institute, Austin Health, (03) 9496 4496, piri@austin.org.au
 Recruitment complete Antenatal depression, cognitive-behavioural therapy, treatment Participants are women aged 18 years or over who are less than 32 weeks pregnant and who meet the Diagnostic and Statistical Manual of Mental Disorders Fourth Edition (DSM-IV) diagnostic criteria for either Major Depression, Minor Depression, Adjustment Disorder with depressed mood, or Adjustment Disorder with mixed anxiety and depressed mood.
HUGS - Early intervention to protect the mother-infant relationship following postnatal depression - a randomised controlled trial ACTRN12612001110875 Parent-Infant Research Institute, Austin Health, (03) 9496 4496, piri@austin.org.au
 Recruitment complete Postnatal depression, mother-infant interaction Women aged 18 years or older with an infant aged 3-9 months and a clinical diagnosis of current major or minor depressive episode
Help-seeking for postnatal depression as a major public health problem: A cluster randomised controlled trial of motivational interviewing ACTRN12611000635965 Parent-Infant Research Institute, Austin Health, (03) 9496 4496, piri@austin.org.au
 Recruitment complete Motivational interviewing, postnatal depression Women with a 4-week old baby
MMB: MumMoodBooster - Web-based cognitive behavioural therapy for women with postnatal depression ACTRN12613000113752 Parent-Infant Research Institute, Heidelberg Repatriation Hospital VIC jeannette.milgrom@austin.org.au Recruitment complete
Omega-3 fatty acids as a treatment for perinatal depression: randomized double-blind placebo-controlled trial Prince Alfred Hospital/University of New South Wales Recruitment complete Social and emotional wellbeing in pregnancy
IFOS - The Infant Fish Oil Supplementation Study ACTRN12606000281594 Princess Margaret Hospital
S J Meldrum		 Recruitment complete Newborn nutrition
Efficacy and safety of a novel fish oil based lipid emulsion (SMOFlipid) compared with olive oil based lipid emulsion (Clinoneic) in term and near-term (>34 weeks) neonates - a randomised controlled trial ACTRN12609000337279 Princess Margaret Hospital for Children, WA girish.deshpande@health.wa.gov.au Recruitment complete Newborn nutrition
QuEST Trial - Questioning the role of egg in lactation for induction of specific tolerance ACTRN12613000643774 Princess Margaret Hospital, Subiaco, WA debbie.palmer@uwa.edu.au Recruitment complete Allergens and epitopes, clinical immunology, food allergy, pediatrics, prevention
Probiotic Allergy Prevention Study ACTRN12606000280505 Princess Margaret Hospital, WA Susan Prescott Recruitment complete
Brief antenatal cognitive behaviour therapy group intervention for the prevention of postnatal depression and anxiety: a randomised controlled trial RHW, Sydney Recruitment complete Parental social and emotional wellbeing
CUT Trial - A prospective, randomised study Comparing cUrved versus straighT scissors to reduce episiotomy extension ACTRN12612000285853 Royal Brisbane & Women's Hospital angela_swift@health.qld.gov.au Recruitment complete Labour and intrapartum care
TIC - Transition from Incubator to Open Cot: early versus late; a randomised, controlled trial PT0427; ACTRN12606000518561 Royal Brisbane & Women's Hospital Karen New Recruitment complete
Perinatal treatment of depression ACTRN12609000831280 Royal Brisbane Hospital Sally Matherson Suspended Parental social and emotional wellbeing
ICE - Infant Cooling Evaluation Trial ACTRN012606000036516; NHMRC216725; PTO367; Royal Children's Hospital , Vic Susan Jacobs Recruitment complete
GAS study - A multisite randomised controlled trial comparing regional and general anaesthesia for effects on neurodevelopmental outcome and apnoea in infants. ACTRN12606000441516 / NCT00756600 Royal Children's Hospital Andrew Davidson Recruitment complete
Baby Biotics: Do probiotics help crying babies and their families? ISRCTN95287767 Royal Children's Hospital Dr Valerie Sung Recruitment complete
Randomised, double-blind, placebo-controlled trial of aminophylline in infants less than 12 months of age with bronchiolitis who require intensive care, to assess if aminophylline is superior to placebo in reducing the duration of ventilatory support ACTRN12608000608369 Royal Children's Hospital, Vic frank.shann@rch.org.au Recruitment complete
IMPRINT - A randomised controlled trial of an adaptive working memory training intervention in very preterm children ACTRN12612000124831 Royal Childrens' Hospital peter.anderson@mcri.edu.au Recruitment complete
Less MAS - Controlled trial of therapeutic lung lavage in meconium aspiration syndrome ACTRN12606000290594/PT0535 Royal Hobart Hospital, Tas Bev Copnell Recruitment complete
OPTIMIST-B - Multicentre randomised controlled trial of minimally-invastive surfactant therapy in preterm infants 29-32 weeks gestation on continuous positive airway pressure ACTRN12611000917932 Royal Hobart Hospital, Tas peter.dargaville@dhhs.tas.gov.au Discontinued Newborn respiratory
FOG Trial - Outpatient Foley catheter vs inpatient Prostin gel for induction of labour ACTRN12609000420246 Royal Hospital for Women amanda.henry@sesiahs.health.nsw.gov.au Recruitment complete Labour and intrapartum care
CiPS - Candida in Pregnancy Study - Treatment of candidiasis to prevent preterm birth - pilot study CiPS pilot ACTRN126090001052224 Royal North Shore Recruitment complete Preterm birth ? prevention and treatment
PDA Trial - Paracetamol Duct Action: The effect of paracetamol vs placebo on ductal closure in premature infants with a late patent ductus arterious ACTRN12611000741987 Royal North Shore Hospital, NSW Prof Martin Kluckow martin.kluckow.usyd.edu.au Recruitment complete PDA closure, Preterm infant, Paracetamol Population: Preterm infants born <33 weeks gestational age with a persistent PDA who are >4 weeks of postnatal age and tolerating at least 50% enteral feeds.
Effect of different diets on gestational diabetes. Can a low glycemic index (GI) diet during pregnancy reduce prevalence of large for gestation age (LGA) amongst gravidas with gestational diabetes (GDM) - a randomised controlled trial ACTRN12608000218392 Royal Prince Alfred Hospital Recruitment complete Diabetes. Maternal nutrition
POP-OUT - Persistent Occiput Posterior: OUTcomes following manual rotation ACTRN12612001312831 Royal Prince Alfred Hospital, NSW hala.phipps@email.cs.nsw.gov.au Recruitment complete
IMPACT reviewed
 Labour and intrapartum care
Perineal outcomes and maternal comfort related to the application of perineal warm packs in the second stage of labor: a randomised controlled trial Royal Prince Alfred Women and Babies, NSW Recruitment complete Labour and intrapartum care
AC/VG BUR Study - Backup rate selection during neonatal assist control volume guarantee ventilation: a randomised crossover trial. ACTRN12610000884000 Royal Women's Hospital
kevin.wheeler@thewomens.org.au		 Recruitment complete Newborn respiratory