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Trial Name Trial ID Main Coordinating Centre
and contact		 Status Recruitment Topic Participants Details
Flows at Lower Rates (FLoRa) - Is bias gas flow in ventilated preterm babies related to lung injury and risk of bronchopulmonary dysplasia? ACTRN12611000628943 Liggins Institute, University of Auckland kittyb@adhb.govt.nz; f.bloomfield@auckland.ac.nz Discontinued Newborn respiratory Babies born at < 28 weeks’ or < 1,000 g needing ventilation in first week of life
FluMum - Maternal influenza vaccination: Improving uptake and evaluating the persistence of immune responses at delivery ANZCTRN12612000175875 Menzies School of Health Research, Charles Darwin University k.ogrady@uq.edu.au Not yet recruiting
FOG Trial - Outpatient Foley catheter vs inpatient Prostin gel for induction of labour ACTRN12609000420246 Royal Hospital for Women amanda.henry@sesiahs.health.nsw.gov.au Recruitment complete Labour and intrapartum care
Foley Catheter Latex versus Silicone for Cervical Ripening Prior to Term Induction of Labour: a randomized controlled trial ACTRN12615000795594 Westmead Hospital; Dr Terry McGee, Terry.McGee@health.nsw.gov.au Currently recruiting Latex; Silicon; Foley catheter This is a prospective randomized clinical trial that is carried out in the Day Assessment Unit and the Birth Unit (the usual sites of Foley catheter insertion) at Westmead Hospital . All women 16 years and over booked for cervical ripening with a Foley catheter before term induction of labour are asked to participate in the study.
Apart from the randomization of catheter material (latex v silicone) all other care will be identical to women not participating in the study.
Folic Acid Clinic Trial (FACT) - Effect of folic acid supplementation in pregnancy on pre-eclampsia ISRCTN23781770; NCT01355159 Ottawa Health Research Institute, Ottawa, Canada bill.hague@adelaide.edu.au Recruitment complete Preeclampsia
FOREMOST trial - Fetal intrapartum pulse oximetry: a multicentre randomised controlled trial PT0360/NHMRC301050/ACTRN012606000307505 Christine East Recruitment complete Labour and intrapartum care
FRUIT-Study - Low-molecular-weight heparin added to aspirin in the prevention of recurrent early-onset pre-eclampsia in women with inheritable thrombophilia ISRCTN87325378 Department of Obstetrics and Gynaecology, VU University Medical Center, Amsterdam,
Netherlands.
Prof JIP de Vries (Chief Investigator) jip.devries@vumc.nl		 Recruitment complete Preeclampsia. Fetal growth. Maternal medical conditions women with previous pregnancy with hypertensive disease and/or SGA <34 weeks and an inheritable thrombophilia
Furosemide for packed red cell transfusion in preterm infants: a randomized controlled trial martin.kluckow@sydney.edu.au Recruitment complete
GAS study - A multisite randomised controlled trial comparing regional and general anaesthesia for effects on neurodevelopmental outcome and apnoea in infants. ACTRN12606000441516 / NCT00756600 Royal Children's Hospital Andrew Davidson Recruitment complete
GEMS - Gestational diabetes trial of detection thresholds: Impact on health and costs ACTRN12615000290594 Liggins Institute, GEMS@auckland.ac.nz Currently recruiting Gestational diabetes, diagnostic thresholds, birthweight Women at >24 weeks’ gestation having a oral glucose tolerance test for gestational diabetes
Gen-D Study - The efficacy of vitamin D supplementation in infants on bone mineral content: A double blind randomized controlled trial ACTRN12613000732785 University of Tasmania Menzies Research Institute Ingrid.vanderMei@utas.edu.au Currently recruiting
Gestational Diabetes: pregnancy outcomes in treatment with metformin compared with insulin MIG PT0521: ACTRN012605000266662 Janet Rowan Recruitment complete Diabetes. Newborn ? developmental
Getting Research into practice - a randomised controlled trial of an educational intervention aimed at increasing the uptake of evidence based guidelines for term prom and for early onset GBS disease J King Recruitment complete
GI Baby 3 - A dietary intervention during pregnancy to reduce child obesity ACTRN12610000681055 The University of Sydney Dawn Tan Recruitment complete Maternal nutrition. Obesity
GluT pilot - Glucose Targets in gestational diabetes Pilot ACTRN12614001250628 Women's and Children's Hospital bill.hague@adelaide.edu.au Currently recruiting Diabetes. Maternal medical conditions Pregnant women with gestational diabetes diagnosed on 75g OGTT: fasting glucose >=5.5 mmol/L and 2h glucose >=8.5 mmol/L, between 12 and 30 weeks gestation, with a singleton or twin pregnancy, not previously diagnosed as diabetic
GRoW - Metformin and dietary advice to improve insulin sensitivity and promote gestational restriction of weight in pregnant women who are obese - a randomised trial ACTRN12612001277831 Discipline of Obstetrics & Gynaecology, The University of Adelaide andrea.deussen@adelaide.edu.au Currently recruiting Obesity. Maternal nutrition Women with a singleton, live gestation between 10 +0 and 20 +0 weeks gestation with a BMI above or equal to 30 kg/m2 at their first antenatal visit.
HATCh - The effects of antenatal hypnosis on pain relief in labour ACTRN12605000018617 / NCT00282204 Women's & Children's Hospital Allan Cyna Recruitment complete Labour and intrapartum care Previous hypnosis for childbirth; woman definitely wants an epidurtal or hypnosis; Not singleton live fetus before 34 weeks gestation; Other conditions causing pain; Active psychiatric illness.
HEADS UP Study. A Randomised Controlled Clinical Trial comparing C-MAC (Trademark) Videolaryngoscope Intubation with Direct Laryngoscope Intubation in Neonates. ACTRN12614001134617 Royal Prince Alfred Hospital, Camperdown Sarah.Bellhouse@sswahs.nsw.gov.au Not yet recruiting
Healthy Living Program after Gestational Diabetes ACTRN12614000539639 Westmead Hospital wah.cheung@sydney.edu.au Recruitment complete
HeLP for Mums - A community based low intensity lifestyle intervention to prevent weight gain in women with children ACTRN12608000110381 Jean Hailes Foundation for Women Health/ Monash University catherine.lombard@monash.edu Recruitment complete
HeLP-her - Healthier lifestyles: Preventing excess weight gain and gestational diabetes in overweight and obese pregnancies: a research and education project ACTRN12608000233325 Jean Hailes Research Group for Womens Health and Monash Institute of Health Services Research (Southern Health)MIMR Recruitment complete Obesity. Diabetes
Help-seeking for postnatal depression as a major public health problem: A cluster randomised controlled trial of motivational interviewing ACTRN12611000635965 Parent-Infant Research Institute, Austin Health, (03) 9496 4496, piri@austin.org.au
 Recruitment complete Motivational interviewing, postnatal depression Women with a 4-week old baby
Helping indigenous women to stop smoking during pregnancy NHMRC320851; ACTRN12609000929202 Sax Institute Sandra Eades Recruitment complete Indigenous maternal/perinatal health. Smoking in pregnancy
HEPRIN - Heparin for the Prevention of complications related to placental Insufficiency ISRCTN88675588 Mt Sinai Hospital, Professor Jodie Dodd (Principal Investigator) jodie.dodd@adelaide.edu.u Recruitment complete Preeclampsia. Fetal growth Women with significant risk factors for placental insufficiency (low PAPP-A, high AFP, high inhibin, high hCG, medical and obstetric risk factors or abdnormal uterine artery Doppler)
HFNP WHO RCT - Pilot randomised control trial of high-flow nasal prong warm, humidified oxygen (HFNP WHO) compared to standard oxygen therapy ACTRN12612000685819 Elizabeth.Kepreotes@hnehealth.nsw.gov.au Recruitment complete
HiFloW Trial - A randomised controlled trial to evaluate the effectiveness of heated, humidified high flow nasal cannula (HHHFNC) in the withdrawal of nasal continuous positive airway pressure (nCPAP) in preterm infants ACTRN12610001003066 RPA Hospital, Sydney david.osborn@email.cs.nsw.gov.au Recruitment complete Newborn respiratory
High flow support versus continuous positive airway pressure (CPAP) support in non-acute respiratory support for preterm infants from 30 weeks corrected gestation ACTRN12610000677000 Ashley McEwan: ashley.mcewan@hotmail.com Recruitment complete Newborn respiratory
HINT - High blood sugar levels and insulin treatment in preterm babies ACTRN12606000270516 Auckland j.alsweiler@adhb.govt.nz Recruitment complete
HINT 2 - Hyperglycaemia in Neonates Trial. Computer determined insulin dosage in the management of neonatal hyperglycaemia ACTRN12614000492651 University of Auckland; Department of Paediatrics: Child and Youth Health, Jane Alsweiler, j.alsweiler@auckland.ac.nz Currently recruiting Neonatal hyperglycaemia, Insulin
 Extremely preterm babies with neonatal hyperglycaemia
HINT Trial - High-flow nasal cannulae versus ambient oxygen for the treatment of newborn infants with early respiratory distress in non-tertiary special care nurseries: a multicentre, randomised controlled trial ACTRN12611000233921 Gosford Hospital and The Royal Women's, Melbourne abuckmaster@nsccahs.health.nsw.gov.au Discontinued Newborn respiratory
HIPERSPACE - Comparing the failure rate of high-flow nasal cannulae (HFNC) versus nasal continuous positive airway pressure (CPAP) as post-extubation respiratory support in premature infants with gestational age of 24 to 32 weeks. ACTRN12610000166077 Royal Women's Hospital, Vic Dr Brett Manley Recruitment complete Newborn respiratory
HIPSTER Trial - High Flow Nasal Cannulae as Primary Support in the Treatment of Early Respiratory Distress ACTRN12613000303741 The Royal Women's Hospital, Vic calum.roberts@thewomens.org.au Recruitment complete
Hominax for improving sperm health ACTRN12616000194460 National Institute of Complementary Medicine, Western Sydney University, Campbelltown Campus, Penrith NSW 2751
Prof Caroline Smith
caroline.smith@westernsydney.edu.au		 Not yet recruiting Reproductive medicine, infertility, male factor Men undergoing fertility treatment
HOPE Trial - Prevention of recurrent pre-eclampsia by folic acid and supplementation in women with hyperhomocysteinaemia PT0362 William Hague Recruitment complete Preeclampsia
hPOD - Hypoglycaemia prevention in newborns with oral dextrose ACTRN12614001263684 Distinguished Prof Jane Harding, Principal Investigator, Liggins Institute, University of Auckland, Private Bag 92019, Auckland 1142, +6493737599 ext 86439, j.harding@auckland.ac.nz

Kelly Fredell, Clinical Research Coordinator, Research Development Coordinator,
Liggins Institute, University of Auckland, Private Bag 92019, Auckland 1142,
+64 9 923 7720 Ext 87720, k.fredell@auckland.ac.nz		 Currently recruiting In newborn infants at risk of hypoglycaemia does prophylactic oral dextrose gel compared to placebo reduce admission to Newborn Intensive Care Unit (NICU) Newborn babies at risk of hypoglycaemia
HUGS - Early intervention to protect the mother-infant relationship following postnatal depression - a randomised controlled trial ACTRN12612001110875 Parent-Infant Research Institute, Austin Health, (03) 9496 4496, piri@austin.org.au
 Recruitment complete Postnatal depression, mother-infant interaction Women aged 18 years or older with an infant aged 3-9 months and a clinical diagnosis of current major or minor depressive episode
HUMBA - Healthy mUMs and Babies Trial. A four-armed randomised controlled demonstration trial of a multifaceted dietary intervention and probiotic capsules in obese pregnant women in the Counties Manukau Health region ACTRN12615000400561 HUMBA room, Community Midwifery area, Building2, Level 2, 19 Lambie Drive,
Manukau, Auckland Contact: Rennae Taylor, Email: r.taylor@auckland.ac.nz		 Currently recruiting Probiotics, Nutritional intervention, Birthweight, Gestational weight gain Non-diabetic obese women with a singleton pregnancy
HUMID Study - A comparison of humidified and unconditioned gases in the delivery room for stabilising preterm infants less than 30 weeks gestation at birth ACTRN12613000093785 The Royal Women's Hospital, Vic lorraine.mcgrory@thewomens.org.au Currently recruiting Newborn resuscitation
HUNTER trial - High-flow nasal cannulae use in non-tertiary centres for early respiratory distress in newborn infants ACTRN12614001203640 Dr Brett Manley, Newborn Research Centre, The Royal Women's Hospital, Parkville, VIC Currently recruiting Neonatology, Respiratory Distress, Preterm Infants, CPAP
 Preterm and term infants admitted to non-tertiary nurseries with respiratory distress
HUUT - Hysterectomy or Uphold Uterine Conservation in women with apical prolapse – a Comparative Trial (HUUT) ACTRN12611000633987 c/o Urodynamic Clinic, 823 - 865 Centre Road, East Bentleigh VIC 3165
alison.leitch@southernhealth.org.au		 Currently recruiting
Hydrocortisone Trial Early adrenal insufficiency in very premature infants PT0364 Helen Liley Recruitment complete
Hypnosis for nausea and vomiting in early pregnancy a randomised controlled trial ACTRN12607000127404 Women's and Children's Hospital Alan Cyna alan.cyna@adelaide.edu.au Recruitment complete Maternal medical conditions Pregnant women suffering from nausea and vomiting of pregnancy.
Hysteroscopic Morcellator versus Electrosurgical resection for Submucosal Leiomyoma ACTRN12615000828527 School of Women's and Children's Health, Level 1, Barker St, Randwick, NSW, 2031 Currently recruiting
I HEAR BETA - Indigenous Healthy EARs- BEtadine, Tissues and Antibiotics. Comparing cotrimoxazole and/or povidone-iodine ear wash with standard dry mopping and ciprofloxacin ear drops in Indigenous children with chronic suppurative otitis media (CSOM) ACTRN12614000234617 Menzies School of Health Research peter.morris@menzies.edu.au Not yet recruiting
ICARIS - Impact of Caesarean Rates following Injections of Sterile Water: a randomised controlled trial ACTRN12611000221954 Mater Health Services nigel.lee@mater.org.au Currently recruiting Labour and intrapartum care
ICE - Infant Cooling Evaluation Trial ACTRN012606000036516; NHMRC216725; PTO367; Royal Children's Hospital , Vic Susan Jacobs Recruitment complete
IDEAL - Dietary and Lifestyle advice for women with borderline gestational glucose intolerance ACTRN12607000174482 Australian Research Centre for Health of Women and Babies (ARCH), The University of Adelaide pat.ashwood@adelaide.edu.au Recruitment complete Diabetes. Maternal nutrition Women between 24 weeks 0 days and 34 weeks 6 days gestation with a singleton pregnancy, with a positive OGCT (venous plasma glucose >=7.8 mmol/L) and a normal 75 gram OGTT (fasting venous plasma glucose <5.5 mmol/L and a 2 hour glucose <7.8 mmol/L),
IFOS - The Infant Fish Oil Supplementation Study ACTRN12606000281594 Princess Margaret Hospital
S J Meldrum		 Recruitment complete Newborn nutrition
IIBAPPA - Intravenous iron versus packed cells in acute post-partum anemia ACTRN12615001370594 Westmead Hospital, Hawkesbury Road, Westmead, NSW 2145
Dr Seng Chua drchuasc@gmail.com 		Not yet recruiting
Immunogenicity and safety of acellular pertussis vaccine given at birth in healthy infants ACTRN12609000905268 Royal Alexandra Hospital for Children, Westmead nicholw3@chrv.edu.au Currently recruiting