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Trial Name Trial ID Main Coordinating Centre
and contact		 Status Recruitment Topic Participants Details
Carbetocin vs oxytocin at emergency caesarean section ACTRN12612000466842 Women's Health Unit, Frankson Hospital, Vic Prof Amar Trivedi Recruitment complete Labour and intrapartum care
N3RO - Can omega 3 fatty acids improve respiratory outcomes in preterm infants? ACTRN12612000503820 Women's & Children's Health Research Institute carmel.collins@health.sa.gov.au Recruitment complete
IMPACT reviewed
 Newborn respiratory Born at less than 29 weeks gestational age, within 3 days of commencing enteral feeds
PPBCR - Parental presence on bedside clinical rounds (PPBCR) in a neonatal intensive care unit (NICU) ACTRN12612000506897 Department of Neonatology, The Canberra Hospital Margaret Broom Recruitment complete
MEAN ITCH Trial - Does methylnaltrexone reduce the incidence and severity of itch following spinal anaesthesia with intrathecal morphine in women undergoing caesarean delivery ACTRN12612000572864 Dept of Anaesthesia & Pain Medicine,<br>King Edward Memorial Hospital for Women michael.paech@health.wa.gov.au Recruitment complete Labour and intrapartum care
STRIDER (NZAus)- A randomised placebo-controlled trial of a new therapy (sildenafil) to help growth in severely growth restricted fetuses at very early gestations ACTRN12612000584831 Department of Obstetrics and Gynaecology, University of Auckland Laura Mackay (Trial Manager) laura.mackay@auckland.ac.nz; Dr Katie Groom (Chief Investigator) k.groom@auckland.ac.nz Recruitment complete
IMPACT reviewed
 Fetal growth. Preeclampsia. Pterterm birth - prevention and treatment Women with pregnancies complicated early onset fetal growth restriction. Abdominal circumference ≤3rd centile at 22-28 weeks or EFW <700g at 28-80 weeks
DIAMIND - Diabetes SMS text reminders versus standard care for women who have had gestational diabetes mellitus to increase the rate of oral glucose testing in the postpartum period ACTRN12612000621819 Australian Research Centre for Health of Women & Babies, The University of Adelaide emer.heatley@adelaide.edu.au Recruitment complete Diabetes. Maternal medical conditions Women with GDM in current pregnancy, singleton or twin pregnancy, with access to a mobile phone, postnatal blood glucose that level returned to normal before discharge
MAMMA -Multidisciplinary Approach to Management of Maternal Asthma ACTRN12612000681853 Mercy Hospital for Women<br>Monash University Johnson.George@monash.edu Recruitment complete Maternal medical conditions
HFNP WHO RCT - Pilot randomised control trial of high-flow nasal prong warm, humidified oxygen (HFNP WHO) compared to standard oxygen therapy ACTRN12612000685819 Elizabeth.Kepreotes@hnehealth.nsw.gov.au Recruitment complete
The Colic, Irritability, Reflux, Intolerance and Allergy Study (CIRIAS) ACTRN12612000773831 University of Queensland, South Brisbane,Tracy Harb, t.harb@uq.edu.au Recruitment complete maternal dietary intervention for colic Mothers of fully breastfed infant <4 months of age with colic
VITAL Trial - The effects of vitamin D supplementation in infancy on immune development ACTRN12612000787886 Childhood Allergy and Immunology Research, University of Western Australia, Dr Debbie Palmer, Ph: + 61 410 851 607, debbie.palmer@uwa.edu.au
 Recruitment complete Vitamin D, infants, immune development Infants with a family history of allergic disease
IMPROVE - Improving Maternal and Progency Obesity Via Exercise: Antenatal exercise in overweight and obese women and its effects on offspring and maternal health ACTRN12612000932864 Liggins institute, The University of Auckland p.hofman@auckland.ac.nz Recruitment complete
A randomised clinical trial at the time of spinal anaesthesia for elective caesarean section to investigate the effect of equipotent phenylephrine and metaraminol infusions on neonatal outcome ACTRN12612000996864 King Edward Memorial Hospital michael.paech@health.wa.gov.au Recruitment complete
RUBY - Ringing Up about Breastfeeding: a randomised control trial exploring earlY telephone peer support for breastfeeding ACTRN12612001024831 Mother & Child Health Research, La Trobe University The Royal Women`s Hospital, Melbourne, Victoria fiona.mclardiehore@thewomens.org.au Recruitment complete Breastfeeding, Peer support 1152 primiparous women with healthy singleton infant born at term, and planning to breastfeed
HUGS - Early intervention to protect the mother-infant relationship following postnatal depression - a randomised controlled trial ACTRN12612001110875 Parent-Infant Research Institute, Austin Health, (03) 9496 4496, piri@austin.org.au
 Recruitment complete Postnatal depression, mother-infant interaction Women aged 18 years or older with an infant aged 3-9 months and a clinical diagnosis of current major or minor depressive episode
BLISS - Baby-led introduction to solids ACTRN12612001133820 University of Otago anne-louise.heath@otago.ac.nz Recruitment complete
Does Vitamin D supplementation in pregnancy improve maternal glucose metabolism or prevent gestational diabetes? ACTRN12612001145897 Westmead Hospital m.mclean@uws.edu.au Recruitment complete
POP-OUT - Persistent Occiput Posterior: OUTcomes following manual rotation ACTRN12612001312831 Royal Prince Alfred Hospital, NSW hala.phipps@email.cs.nsw.gov.au Recruitment complete
IMPACT reviewed
 Labour and intrapartum care
A randomised controlled trial comparing immediate and controlled release oxycodone the day after caesarean section ACTRN12613000076774 Ipswich Hospital, QLD Anthony_Schoenwald@health.qld.gov.au Recruitment complete
MMB: MumMoodBooster - Web-based cognitive behavioural therapy for women with postnatal depression ACTRN12613000113752 Parent-Infant Research Institute, Heidelberg Repatriation Hospital VIC jeannette.milgrom@austin.org.au Recruitment complete
Dietary modification for asthma control in pregnancy ACTRN12613000301763 The University of Adelaide/Robinson Research Inst vicki.clifton@adelaide.edu.au Recruitment complete
HIPSTER Trial - High Flow Nasal Cannulae as Primary Support in the Treatment of Early Respiratory Distress ACTRN12613000303741 The Royal Women's Hospital, Vic calum.roberts@thewomens.org.au Recruitment complete
pre-hPOD - Hypoglycaemia prevention in newborns with oral dextrose ACTRN12613000322730 Liggins Insitute, University of Auckland Dr Jo Hegarty: j.hegarty@auckland.ac.nz Recruitment complete
The prophylactic use of a Bakri balloon for women undergoing caesarean section for placenta praevia - a randomised controlled trial Bakri ACTRN12613000348752 Mater Mothers' Research Centre/Mater Health Services Michael Beckmann Recruitment complete Labour and intrapartum care
ARRIVaL - Artificial Rupture of membranes versus Repeat Intra-Vaginal prostaglandins for induction of labour: a randomised controlled trial ACTRN12613000370707 Mater Mothers` Research Centre, Mater Health Services michael.beckmann@mater.org.au Recruitment complete Labour and intrapartum care
QuEST Trial - Questioning the role of egg in lactation for induction of specific tolerance ACTRN12613000643774 Princess Margaret Hospital, Subiaco, WA debbie.palmer@uwa.edu.au Recruitment complete Allergens and epitopes, clinical immunology, food allergy, pediatrics, prevention
MBB - A pilot study to test recruitment methods, feasibility and study procedures for a planned randomised controlled trial of the MindBabyBody program: an antenatal mindfulness intervention to reduce depression, stress and anxiety ACTRN12613000742774 The Royal Women's Hospital, Parkville, Vic hannah.woolhouse@mcri.edu.au Recruitment complete
A randomised controlled trial of Baby Triple P: an evaluation of an antenatal parenting program to improve parental responsiveness in first-time parents ACTRN12613000948796 School of Psychology, University of Queensland mandy.mihelic@uq.net.au Recruitment complete
NIFTY - A multi-centre randomised double blind placebo controlled trial of nifedipine maintenance tocolysis in fetal fibronectin positive women in threatened preterm labour ACTRN12613000985785 National Women's Health, Auckland Hospital. Dr Emma Parry (Principal Investigator) EmmaP@adhb.govt.nz Recruitment complete Preterm birth ? prevention and treatment Women with threatened preterm labour, a singleton pregnancy, gestational age between 24 and 34 weeks, intact membranes, positive fetal fibronectin test, completed course of corticosteroids
CROPP - Controlled Released Oxycodone for post caesarean section pain relief.Comparing oral and intravenous patient controlled analgesia for post caesarean section pain relief: a randomised controlled trial ACTRN12613001011774 Toowoomba Hospital, QLD pierrekotze1@gmail.com Recruitment complete
A randomised controlled trial comparing daily (400 IU) and single bolus dosing (50,000 IU) of vitamin D in healthy breastfed infants of vitamin D deficient mothers ACTRN12613001234707 Sunshine Hospital
julie.huynh@wh.org.au; christine.rodda@unimelb.edu.au		 Recruitment complete
txt4two - Testing the feasibility of an intervention program to promote healthy nutrition, physical activity and weight gain in pregnant women ACTRN12614000288628 Dr Jane Wilcox, School of Exercise and Nutrition Sciences, Deakin University jwillcox@deakin.edu.au Recruitment complete Gestational weight gain, mHealth, nutrition
 Eligible women were identified at their first hospital antenatal visit to a university-affiliated maternity hospital in Melbourne, Australia. Eligibility criteria included women with a singleton, live gestation between 10+0-17+6 weeks; self-reported pre-pregnancy BMI>25kg/m2; able to speak, read and write English; and owned a mobile phone.
Incentives to stop smoking among pregnant Maori women: A feasibility trial Awhi-Incentives ACTRN12614000520639 University of Auckland m.glover@auckland.ac.nz Recruitment complete
The effects of mindfulness training on maternal stress, depressed mood and present moment awareness: A pilot randomised trial ACTRN12614000523606 Monash University jill.beattie@monash.edu Recruitment complete Mindfulness, Pregnancy, Randomised trial Low risk pregnancy in the second trimester at the start of the intervention; 18 years or older; able to read and speak English; having a planned hospital birth; and who commit to attending all eight sessions.
Healthy Living Program after Gestational Diabetes ACTRN12614000539639 Westmead Hospital wah.cheung@sydney.edu.au Recruitment complete
PIFI - Parent Infant Feeding Initiative: a study to enhance breastfeeding duration ACTRN12614000605695 Curtin University, Perth, Western Australia. Prof Jane Scott jane.scott@curtin.edu.au Recruitment complete Health promotion/education; Breastfeeding Expectant couples (mothers and fathers)
FLIP - Flavour for Infants born Preterm. Taste and Smell to improve milk tolerance in preterm infants ACTRN12614000661673 Mercy Hospital for Women, Vic fbeker@web.de Recruitment complete
A pilot randomised controlled trial to determine the effect of a physiological (step) versus a standard action (slope) labour progress lines on the rate of spontaneous vaginal birth amongst low risk women in labour for the first time ACTRN12614000786695 Midwifery Research Unit, Mater Research Institute
nigel.lee@mater.org.au		 Recruitment complete
Novel feeding system to promote the establishment of breastfeeding after preterm birth a randomised controlled trial ACTRN12614000875606 University of Western Australia karen.simmer@health.wa.gov.au Recruitment complete
The evaluation of two types of pelvic support belt commonly used in the treatment of pubic symphysis pain to assess their comfort and symptom relief in pregnant New Zealand women; a pilot study ACTRN12614000898651 University of Otago stephanie.woodley@anatomy.otago.ac.nz Recruitment complete
e-prem - Improving child and parent outcomes after preterm birth using a web-based early intervention program ACTRN12614000906651 Murdoch Childrens Research Institute karli.treyvaud@mcri.edu.au Discontinued
A randomised controlled trial of a brief multi strategic child health nurse intervention to reduce infant secondhand smoke exposure ACTRN12614001032640 Hunter New England Health justine.daly@hnehealth.nsw.gov.au Recruitment complete
PRIVA Trial - A comparison of the overall pain scores post caesarean section, when initial intraoperative analgesia is given intravenously (IV) versus per rectum (PR) ACTRN12614001144606 dlowen@gmp.usyd.edu.au Recruitment complete
AcuAnteDep - A pragmatic randomised controlled trial evaluating acupuncture as an antenatal intervention for the treatment of antenatal depression ACTRN12615000250538 NICM, Western Sydney University, caroline.smith@uws.edu.au Recruitment complete Antenatal depression, acupuncture, treatment Depressed pregnant women scoring 13 or more on the EDS at 24 weeks gestation
The Motherhood Choices Decision Aid for Women with Rheumatoid Arthritis Increases Knowledge and Reduces Decisional Conflict: A Randomized Controlled Study ACTRN12615000523505 School of Social Science and Psychology, University of Western Sydney t.meade@uws.edu.au Recruitment complete
Developing an educational intervention for high risk women with Gestational Diabetes Mellitus (Eat for your baby) ACTRN12615000697583 Victoria University College of Health and Biomedicine mary.carolan@vu.edu.au Recruitment complete
ACTS - Australasian Collaborative Trial of vitamin C and E supplementation for the prevention of pre-eclampsia ISRCTN00416244/NCT00097110/NHMRC207744 caroline.crowther@adelaide.edu.au Recruitment complete Preeclampsia. Maternal nutrition. Maternal medical conditions Nulliparous women with a singleton pregnancy, between 14-22 weeks gestation, a normal blood pressure
PRISM - Program of Resources, Information and Support for Mothers ISRCTN03464021; NHMRC191215; PT0523 La Trobe University (Australia): Prof Judith Lumley Recruitment complete
CHOPP (Childhood Obesity Primary Prevention) Study - A pregnancy intervention to reduce postprandial glucose excursions in the primary prevention of paediatric obesity ISRCTN10344179 j.brandmiller@mmb.usyd.edu.au Discontinued
Does telephone peer support and/or a midwife home visit in the early postnatal period increase breastfeeding duration? ISRCTN17386721 d.forster@latrobe.edu.au Discontinued Breastfeeding. Parental social and emotional wellbeing
PROGRESS - Australian Collaborative trial of vaginal progesterone for prevention of neonatal respiratory distress syndrome ISRCTN20269066; NHMRC399137 Maternal Perinatal Clinical Trials Unit, Adelaide Women's and Children's Pat Ashwood Recruitment complete Preterm birth ? prevention and treatment. Preterm birth ? improving outcomes (antenatal interventions). Newborn respiratory Pregnant women with a history of prior spontaneous preterm birth at less than 34 weeks gestation