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Trial Name Trial ID Main Coordinating Centre
and contact		 Status Recruitment Topic Participants Details
Brief antenatal cognitive behaviour therapy group intervention for the prevention of postnatal depression and anxiety: a randomised controlled trial RHW, Sydney Recruitment complete Parental social and emotional wellbeing
PRIME - The effect of midwife-led counselling on mental health outcomes for women experiencing a traumatic childbirth: a randomised controlled trial ACTRN12610000098033 j.gamble@griffith.edu.au Recruitment complete Parental social and emotional wellbeing
Perinatal treatment of depression ACTRN12609000831280 Royal Brisbane Hospital Sally Matherson Suspended Parental social and emotional wellbeing
Effect of the 'Mother and Baby' program on new mothers' psychological and physical well-being NCT00361478 The Angliss Hospital, Vic Recruitment complete Parental social and emotional wellbeing
Three model care pathways for postnatal depression NCT01002027 Austin Health, Vic Jeanette Milgrom Recruitment complete Parental social and emotional wellbeing
Baby Business: the first few months of life. The impact of a brief universal parenting program to prevent early infant sleep and cry problems and associated parental depression: a randomised controlled trial ISRCTN63834603 Centre for Community Child Health, Royal Children's Hospital Dr Harriet Hiscock Recruitment complete Parental social and emotional wellbeing
The virtual infant parenting program: a randomised controlled trial ISRCTN24952438 Centre for Devel Health, Curtin Heath Innov Res Inst, Curtin University of Technology Prof Sven Silburn Recruitment complete Parental social and emotional wellbeing
MoodGYM - Online cognitive behaviour therapy (MoodGYM) for the prevention of postnatal depression in at-risk mothers: a randomised controlled trial ACTRN12609001032246 Centre for Mental Health Research, The Australian National University bethany.jones@anu.edu.au Currently recruiting Parental social and emotional wellbeing
MobileMums: a randomized controlled trial of an SMS -based physical activity intervention. Recruitment complete Parental social and emotional wellbeing
Fighting obesity from conception- a randomised trial ACTRN12605000709640; PT0543 Julie Quinlivan Recruitment complete Obesity. Maternal nutrition
GRoW - Metformin and dietary advice to improve insulin sensitivity and promote gestational restriction of weight in pregnant women who are obese - a randomised trial ACTRN12612001277831 Discipline of Obstetrics & Gynaecology, The University of Adelaide andrea.deussen@adelaide.edu.au Currently recruiting Obesity. Maternal nutrition Women with a singleton, live gestation between 10 +0 and 20 +0 weeks gestation with a BMI above or equal to 30 kg/m2 at their first antenatal visit.
LIMIT - Limiting weight gain in overweight and obese women during pregnancy to improve health outcomes: a randomised trial ACTRN12607000161426 Women's and Children's Hospital Andrea Deussen Recruitment complete Obesity. Maternal nutrition Pregnant women with a singleton, live gestation between 10+0 - 20 weeks who are obese or overweight (defined as a body mass index greater that 25kg/m2)
SPRING - Probiotics for the prevention of gestational diabetes in overweight and obese women ACTRN12611001208998 Royal Brisbane and Women`s Hospital, QLD l.callaway@uq.edu.au Not yet recruiting Obesity. Diabetes
HeLP-her - Healthier lifestyles: Preventing excess weight gain and gestational diabetes in overweight and obese pregnancies: a research and education project ACTRN12608000233325 Jean Hailes Research Group for Womens Health and Monash Institute of Health Services Research (Southern Health)MIMR Recruitment complete Obesity. Diabetes
The impact of continuity of care on weight gain in obese pregnant women ACTRN12610001078044 Deakin University cate.nagle@deakin.edu.au Currently recruiting Obesity
Weighing pregnant women to achieve ideal weight gains in pregnancy ACTRN12607000272493 Mercy Hospital Recruitment complete Obesity
Supervised home-based exercise may attenuate the decline of glucose tolerance in obese pregnant women Assoc/Prof Kym Guelfi Recruitment complete Obesity
ProNose study - A randomised trial of a nasal barrier dressing to reduce nasal trauma in very preterm infants receiving continuous positive airway pressure (CPAP) or nasal intermittent positive pressure ventilation (NIPPV) treatment ACTRN12616000438459 The Royal Women's Hospital ; Level 7, 20 Flemington Road; Parkville, VIC 3052; Australia
Dr Brett Manley
brett.manley@thewomens.org.au		 Currently recruiting Newborn, respiratory, preterm, nasal trauma Preterm newborns
SCION trial - Evaluation of automated control of oxygen therapy in extremely preterm infants ACTRN12616000301460 Dept of Paediatrics, Royal Hobart Hospital, Hobart, TAS 7000
Prof Peter Dargaville
peter.dargaville@dhhs.tas.gov.au		 Not yet recruiting Newborn, respiratory, extremely preterm infants Extremely preterm newborns
A randomised controlled trial of the use of a respiratory function monitor to teach neonatal mask ventilation to healthcare professionals in a simulation setting ACTRN12616000542493 Newborn Research Centre, Royal Women's Hospital, VIC 3052
Dr Eoin O Currain
eoin.ocurrain@thewomens.org.au		 Not yet recruiting Newborn, respiratory, clinician training Healthcare professionals
EPAR study - Early PARacetamol (EPAR) to promote early closure of the ductus arteriosus in preterm infants ACTRN12616001517460 Department of Newborn Care, Royal Hospital for Women, Barker St, Randwick NSW 2031
Dr Timothy Schindler
tschindl@med.usyd.edu.au		 Currently recruiting Newborn, preterm, ductus arteriosus Preterm newborns
SO3 trial - Can omega-3 fatty acids reduce cardiovascular risk in children born with poor fetal growth: the Small baby Omega-3 ACTRN12616000053426 Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders, The University of Sydney, Camperdown, NSW 2006
A/Prof Michael Skilton
michael.skilton@sydney.edu.au		 Not yet recruiting Newborn, nutrition, small-for-gestational-age Newborns, small for gestational age
TASTE - Effect of smell and taste to improve nutrition in very preterm babies ACTRN12617000583347 Neonatal Critical Care Unit, Mater Mothers' Hospital, QLD 4101
Dr Friederike Beker
friederike.beker@mater.org.au		 Currently recruiting Newborn, nutrition, preterm, tube feeding Very preterm newborns
PAEAN - Preventing Adverse Outcomes of Neonatal Hypoxic Ischaemic Encephalopathy with Erythropoietin: a randomised placebo controlled multicentre clinical trial ACTRN12614000669695 NHMRC Clinical Trials Centre, University of Sydney

paean@ctc.usyd.edu.au

+61 2 9562 5000

 Currently recruiting
IMPACT reviewed
 Newborn – developmental
CIRCA DIEM ACTRN12618000371291p Jane Pillow
+61417621960
jane.pillow@uwa.edu.au
The University of Western Australia		 Not yet recruiting
IMPACT endorsed
 Newborn – developmental
 Babies born at < 31 weeks and 6 days postmenstrual age. Have initial care at a perinatal centre where routine care does not include individual environmental light/noise cycling.
VINE Study - Videolaryngoscopy for Intubation of Neonates: an Evaluation - a randomised controlled study ACTRN12613000159752 Department of Newborn Research, Royal Women's Hospital, Vic joyce.oshea@thewomens.org.au Not yet recruiting Newborn resuscitation. Newborn respiratory
HUMID Study - A comparison of humidified and unconditioned gases in the delivery room for stabilising preterm infants less than 30 weeks gestation at birth ACTRN12613000093785 The Royal Women's Hospital, Vic lorraine.mcgrory@thewomens.org.au Currently recruiting Newborn resuscitation
To2rpido Study - Targeted Oxygenation in the Resuscitation of Premature Infants and their Developmental Outcome. (formally recorded as) Feasibility of Multinational Trial of Targeted Oxygen for the Resuscitation of Premature Infants and their Development ACTRN12610001059055 Dept of Newborn Care, Royal Hospital for Women, NSW ju.oei@sesiahs.health.nsw.gov.au Currently recruiting Newborn resuscitation
MONT (mask or nasal tube) Trial: A randomised controlled trial of mask versus nasal tube for the stabilisation of preterm infants (born between 24 and 29 complete weeks gestation) in the delivery room ACTRN12610000230055; NTR2061 Newborn Services and Neonatal Research, Royal Women's Hospital Omar Kamlin Recruitment complete Newborn resuscitation
A comparison of Propofol and Suxamethonium as induction agents for neonatal endotracheal intubation PT0545 Julee Oei Recruitment complete Newborn respiratory. Newborn resuscitation
The effects of nasal continuous positive airway pressure on cardiac function in (i) premature infants with established lung disease and (ii) premature infants with minimal lung disease. ACTRN12611001057976 Royal Women's Hospital, Vic sheryle.rogerson@the womens.org.au Recruitment complete Newborn respiratory. Newborn cardiovascular
EVARO study (Enteral vitamin A to improve Respiratory Outcomes) Oral vitamin A for prevention of bronchopulmonary dysplasia in extremely preterm infants: a randomised controlled trial ACTRN12616000408482 Department of Neonatal Paediatrics, King Edward Memorial Hospital, Subiaco, WA 6008
Dr Abhijeet Rakshasbhuvankar
abhijeet.rakshasbhuvankar@health.wa.gov.au		 Currently recruiting Newborn respiratory, extremely preterm, chronic lung disease prevention Extremely preterm newborns
PLUSS - Preventing Chronic Lung Disease in Extremely Preterm Infants Using Surfactant + Steroid ACTRN12617000322336 Newborn Research Centre, The Royal Women's Hospital, Parkville, Victoria 3052
Dr Omar Kamlin
omar.kamlin@thewomens.org.au		 Not yet recruiting Newborn respiratory, extremeley low birthweight, chronic lung disease prevention Extremely preterm newborns
OPTIMIST-B - Multicentre randomised controlled trial of minimally-invastive surfactant therapy in preterm infants 29-32 weeks gestation on continuous positive airway pressure ACTRN12611000917932 Royal Hobart Hospital, Tas peter.dargaville@dhhs.tas.gov.au Discontinued Newborn respiratory
AC/VG Flow Study - Ventilator circuit flow selection during neonatal assist control volume guarantee ventilation: a randomised crossover trial. ACTRN12610000885099 Kevin Wheeler Recruitment complete Newborn respiratory
AC/VG Pmax Study - Pressure limit selection during neonatal assist control volume guarantee ventilation: A randomised crossover trial. ACTRN12610000886088 kevin.wheeler@thewomens.org.au Recruitment complete Newborn respiratory
The effect of sildenafil in preterm infants with evolving chronic lung disease NCT00431418 kkonig@mercy.com.au Recruitment complete Newborn respiratory
HIPERSPACE - Comparing the failure rate of high-flow nasal cannulae (HFNC) versus nasal continuous positive airway pressure (CPAP) as post-extubation respiratory support in premature infants with gestational age of 24 to 32 weeks. ACTRN12610000166077 Royal Women's Hospital, Vic Dr Brett Manley Recruitment complete Newborn respiratory
AC/VG BUR Study - Backup rate selection during neonatal assist control volume guarantee ventilation: a randomised crossover trial. ACTRN12610000884000 Royal Women's Hospital
kevin.wheeler@thewomens.org.au		 Recruitment complete Newborn respiratory
In very preterm infants who are being extubated to nasal continuous positive airway pressure (CPAP), does a continuous positive airway pressure (CPAP) recruitment maneuvre post extubation improve global and regional end-expiratory lung volume CPAP Study ACTRN12610000167066 Royal Women's Hospital, Vic risha.bhatia@thewomens.org.au Currently recruiting Newborn respiratory
HiFloW Trial - A randomised controlled trial to evaluate the effectiveness of heated, humidified high flow nasal cannula (HHHFNC) in the withdrawal of nasal continuous positive airway pressure (nCPAP) in preterm infants ACTRN12610001003066 RPA Hospital, Sydney david.osborn@email.cs.nsw.gov.au Recruitment complete Newborn respiratory
CAP Trial - Caffeine for Apnea of Prematurity Trial PT0357 Peter Davis Recruitment complete Newborn respiratory
N3RO - Can omega 3 fatty acids improve respiratory outcomes in preterm infants? ACTRN12612000503820 Women's & Children's Health Research Institute carmel.collins@health.sa.gov.au Recruitment complete
IMPACT reviewed
 Newborn respiratory Born at less than 29 weeks gestational age, within 3 days of commencing enteral feeds
HINT Trial - High-flow nasal cannulae versus ambient oxygen for the treatment of newborn infants with early respiratory distress in non-tertiary special care nurseries: a multicentre, randomised controlled trial ACTRN12611000233921 Gosford Hospital and The Royal Women's, Melbourne abuckmaster@nsccahs.health.nsw.gov.au Discontinued Newborn respiratory
RHINO - A study of intranasal remifentanil for intubation and surfactant administration in neonates ACTRN12612000386831 John Hunter Children's Hospital, NSW Ian.Wright@hnehealth.nsw.gov.au Not yet recruiting Newborn respiratory
CureNeb - Aerosolized surfactant in the first hour of life ACTRN12610000857000 King Edward Memorial Hospital Dr Stefan Minocchieri/Prof J J Pillow Discontinued Newborn respiratory
Flows at Lower Rates (FLoRa) - Is bias gas flow in ventilated preterm babies related to lung injury and risk of bronchopulmonary dysplasia? ACTRN12611000628943 Liggins Institute, University of Auckland kittyb@adhb.govt.nz; f.bloomfield@auckland.ac.nz Discontinued Newborn respiratory Babies born at < 28 weeks’ or < 1,000 g needing ventilation in first week of life
High flow support versus continuous positive airway pressure (CPAP) support in non-acute respiratory support for preterm infants from 30 weeks corrected gestation ACTRN12610000677000 Ashley McEwan: ashley.mcewan@hotmail.com Recruitment complete Newborn respiratory
Targeted Delivery Suite Intervention Study (TARDIS). A randomised controlled trial of modes of ventilatory support in preterm babies from point of delivery to the neonatal intensive care unit ACTRN12609000986279 Nepean Hospital mark.tracy@swahs.health.nsw.gov.au Currently recruiting Newborn respiratory
DINO trial - Docosahexaenoic acid (DHA) for the improvement of neurodevelopmental outcome in preterm infants PT0424/NHMRC250322/ACTRN12606000327583 Women's and Children's Hospital Suzanne McCusker Recruitment complete Newborn nutrition. Newborn ? developmental Infants born < or = 32 weeks gestation