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Trial Name Trial ID Main Coordinating Centre
and contact		 Status Recruitment Topic Participants Details
A randomised clinical trial at the time of spinal anaesthesia for elective caesarean section to investigate the effect of equipotent phenylephrine and metaraminol infusions on neonatal outcome ACTRN12612000996864 King Edward Memorial Hospital michael.paech@health.wa.gov.au Recruitment complete
Optimisation of the management of placental delivery in second trimester pregnancy interruption NCT00120042 King Edward Memorial Hospital, WA Jan Dickinson Recruitment complete
A prospective randomised trial to study the effect of intravenous iron therapy versus the standard treatment with oral iron for women diagnosed with iron deficiency anaemia in pregnancy ACTRN12609000177257 Launceston General Hospital
joanne.bates@dhhs.tas.gov.au		 Recruitment complete Maternal nutrition At risk women - dark skinned, veiled, Anyone with vitamin D deficiency that has not commenced treatment prior to recruitment
pre-hPOD - Hypoglycaemia prevention in newborns with oral dextrose ACTRN12613000322730 Liggins Insitute, University of Auckland Dr Jo Hegarty: j.hegarty@auckland.ac.nz Recruitment complete
IMPROVE - Improving Maternal and Progency Obesity Via Exercise: Antenatal exercise in overweight and obese women and its effects on offspring and maternal health ACTRN12612000932864 Liggins institute, The University of Auckland p.hofman@auckland.ac.nz Recruitment complete
World Maternal Antifibrinolytic Trial (WOMAN) - Tranexamic acid for the treatment of postpartum haemorrhage: an international, randomised, double blind, placebo controlled trial. ISRCTN76912190/ NCT00872469 Clinical Trials Unit, London School of Hygiene and Tropical Medicine
thewomantrial@lshtm.ac.uk, http://www.womantrial.lshtm.ac.uk/
 Recruitment complete Maternal Health, Postpartum Haemorrhage Adult women, after delivery who have clinically diagnosed postpartum haemorrhage, are eligible if the responsible doctor is for any reason substantially uncertain whether or not to use an antifibrinolytic agent. 20 060 women were enrolled by the end of the trial.
The Healthy Start to Pregnancy study - an evaluation of a new early antenatal health promotion model of care for improving maternal health behaviours ACTRN12611000867998 Mater Medical Research Institute Dr Shelley Wilkinson Recruitment complete Social and emotional wellbeing in pregnancy
Ultrasound guided transverses abdominis plane (TAP) block for analgesia after caesarean surgery ACTRN12608000540314 Mater Misericordiae Health Services Brisbane Ltd Phillip Cowlishaw Recruitment complete
SWITCh - A randomised, controlled trial of a single versus a four intradermal Sterile Water Injection Technique for relief of Continuous lower back pain during labour ACTRN12609000964213 Mater Mothers' Hospital nigel.lee@mater.org.au Recruitment complete Labour and intrapartum care
LOS trial - Prevention of late onset septicemia in infants in the neonatal intensive care unit, Mater Mothers' Hospital. PT0363 Mater Mothers' Hospital, Brisbane Helen Liley Recruitment complete Newborn infection
WILD A - Women and the Induction of Labour Dilemma-Trial A PT0519 Mater Mothers Hospital, Brisbane Paul Devenish-Meares Recruitment complete
The prophylactic use of a Bakri balloon for women undergoing caesarean section for placenta praevia - a randomised controlled trial Bakri ACTRN12613000348752 Mater Mothers' Research Centre/Mater Health Services Michael Beckmann Recruitment complete Labour and intrapartum care
ARRIVaL - Artificial Rupture of membranes versus Repeat Intra-Vaginal prostaglandins for induction of labour: a randomised controlled trial ACTRN12613000370707 Mater Mothers` Research Centre, Mater Health Services michael.beckmann@mater.org.au Recruitment complete Labour and intrapartum care
PROGRESS - Australian Collaborative trial of vaginal progesterone for prevention of neonatal respiratory distress syndrome ISRCTN20269066; NHMRC399137 Maternal Perinatal Clinical Trials Unit, Adelaide Women's and Children's Pat Ashwood Recruitment complete Preterm birth ? prevention and treatment. Preterm birth ? improving outcomes (antenatal interventions). Newborn respiratory Pregnant women with a history of prior spontaneous preterm birth at less than 34 weeks gestation
BAC - Birth after Caesarean. Planned vaginal birth or planned caesarean section for women at term with a single previous caesarean birth ISRCTN53974531/NHMRC349460 Maternal Perinatal Clinical Trials Unit, Adelaide Women's and Children's
Pat Ashwood		 Recruitment complete Labour and intrapartum care Women with a single prior caesarean presenting in their next pregnancy with a single live fetus in cephalic presentation who have reached 37 weeks gestation, and who don't have a contraindication to a planned VBAC.
EECV2 - Early external cephalic version 2 trial PT0542/ISRCTN56498577 McMaster, Canada Eileen Hutton Recruitment complete Models of care
InFANT - The Infant Feeding Activity and Nutrition Trial an early intervention to prevent childhood obesity: cluster-randomised controlled trial ISRCTN81847050 Melbourne Dr Karen Campbell Recruitment complete Newborn nutrition
PneuMum - Pneumococcal Vaccination of Australian Indigenous Mothers to See if it Protects their babies from Ear Disease NCT00310349; NCT00714064 Menzies School of Health Research Amanda Leach Recruitment complete
STRIDER (NZAus)- A randomised placebo-controlled trial of a new therapy (sildenafil) to help growth in severely growth restricted fetuses at very early gestations ACTRN12612000584831 Department of Obstetrics and Gynaecology, University of Auckland Laura Mackay (Trial Manager) laura.mackay@auckland.ac.nz; Dr Katie Groom (Chief Investigator) k.groom@auckland.ac.nz Recruitment complete
IMPACT reviewed
 Fetal growth. Preeclampsia. Pterterm birth - prevention and treatment Women with pregnancies complicated early onset fetal growth restriction. Abdominal circumference ≤3rd centile at 22-28 weeks or EFW <700g at 28-80 weeks
A family tobacco control program to reduce respiratory illness in Indigenous infants. ACTRN12609000397213 Menzies School of Health Research/Royal Darwin Hospital Vanessa Johnston Recruitment complete Smoking in pregnancy. Indigenous maternal/perinatal health
PRISM - Program of Resources, Information and Support for Mothers ISRCTN03464021; NHMRC191215; PT0523 La Trobe University (Australia): Prof Judith Lumley Recruitment complete
Weighing pregnant women to achieve ideal weight gains in pregnancy ACTRN12607000272493 Mercy Hospital Recruitment complete Obesity
RUCC - RCT of Umbilical Cord Clamping Recruitment complete
Randomised controlled trial to compare heated humidified high-flow nasal cannulae with nasal continuous positive airway pressure postextubation in premature infants Mercy Hospital for Women c.collins@mercy.com.au Recruitment complete
Effect of omeprazole on acid gastroesophageal reflux and gastric acidity in preterm infants with pathological acid reflux Recruitment complete
DAME - Diabetes & antenatal milk expressing: a pilot/feasibility study Mercy Hospital for Women Kerri McEgan Recruitment complete
Enteral glucose and electrolyte solution versus IV fluids Recruitment complete
ELVIS - A Randomised Controlled Trial Investigating the Influence of BCG (Bacillus Calmette-Gu NCT02444611 Mercy Hospital for Women, Heidelberg lianne.cox@rch.org.au Recruitment complete
Accuracy of clinical assessment of infant heart rate in the delivery room Recruitment complete
FFF - The effect of regular weighing and dietary advice on maternal health and complications of pregnancy in overweight pregnant women: Facts, figures and feelings about weight gain in pregnancy ACTRN12611000881932 Mercy Hospital for Women, Heidelberg, Vic ashub@mercy.com.au Recruitment complete
A randomised crossover trial of two algorithms for managing desaturation episodes in ventilated premature infants Recruitment complete
Cervical occlusion in women with cervical insufficiency: randomised, controlled trial with cerclage, with and without cervical occlusion NCT01737788 Recruitment complete Preterm birth ? prevention and treatment
FLIP - Flavour for Infants born Preterm. Taste and Smell to improve milk tolerance in preterm infants ACTRN12614000661673 Mercy Hospital for Women, Vic fbeker@web.de Recruitment complete
CHIPS trial: Control of Hypertension In Pregnancy Study ISRCTN71416914 / NCT01192412 Recruitment complete Maternal medical conditions. Preeclampsia
MAMMA -Multidisciplinary Approach to Management of Maternal Asthma ACTRN12612000681853 Mercy Hospital for Women<br>Monash University Johnson.George@monash.edu Recruitment complete Maternal medical conditions
FLORIAN - In extremely low birth weight (ELBW) infants who require positive pressure at birth does the use of a respiratory Function Monitor reduce face mask leak and improve the target tidal volume in the first ten minutes of life? ACTRN12608000357358 The Royal Women's Hospital, Melbourne: georg.schmoelzer@thewomens.org.au Recruitment complete
Targeting duration of indomethacin treatment to the PDA constrictive response using echocardiography: a randomised controlled trial Recruitment complete Newborn cardiovascular
A comparison of two nasal continuous positive airway pressure interfaces - a randomized crossover study Middlemore Hospital/Univ of Auckland NZ
mmeyer@middlemore.co.nz		 Recruitment complete
SUPPOSE - Randomised controlled trial of prophylactic glycerol suppositories on gastric emptying and feed tolerance in premature infants Recruitment complete Newborn nutrition
A pilot randomised controlled trial to determine the effect of a physiological (step) versus a standard action (slope) labour progress lines on the rate of spontaneous vaginal birth amongst low risk women in labour for the first time ACTRN12614000786695 Midwifery Research Unit, Mater Research Institute
nigel.lee@mater.org.au		 Recruitment complete
A randomised controlled trial on the effects of antenatal vitamin D supplementation to improve vitamin D levels in the maternal and cord blood at birth in vitamin D deficient pregnant women ACTRN12609000142235 Monash Medical Centre Recruitment complete Maternal nutrition
Efficacy and safety of Insulin Detemir versus NPH insulin in pregnant women with type 1 diabetes NCT00474045 Recruitment complete Diabetes
Study evaluating pantoprazole in neonates and preterm infants with GERD NCT00362609 Recruitment complete
Efficacy and safety of esomeprazole once daily for the treatment of GERD in neonatal patients NCT00427635 Recruitment complete
MobileMums: a randomized controlled trial of an SMS -based physical activity intervention. Recruitment complete Parental social and emotional wellbeing
Determining the best method of Nellcor pulse oximeter sensor application in neonates Recruitment complete
Walking versus lying to prevent hypotension following spinal anaesthesia for caesarean section ACTRN12606000391572 allan Cyna Recruitment complete Labour and intrapartum care. Maternal medical conditions Pregnant women having spinal anaesthesia prior to caesarean section
The effects of mindfulness training on maternal stress, depressed mood and present moment awareness: A pilot randomised trial ACTRN12614000523606 Monash University jill.beattie@monash.edu Recruitment complete Mindfulness, Pregnancy, Randomised trial Low risk pregnancy in the second trimester at the start of the intervention; 18 years or older; able to read and speak English; having a planned hospital birth; and who commit to attending all eight sessions.
RUBY - Ringing Up about Breastfeeding: a randomised control trial exploring earlY telephone peer support for breastfeeding ACTRN12612001024831 Mother & Child Health Research, La Trobe University The Royal Women`s Hospital, Melbourne, Victoria fiona.mclardiehore@thewomens.org.au Recruitment complete Breastfeeding, Peer support 1152 primiparous women with healthy singleton infant born at term, and planning to breastfeed
DAME - Diabetes and antenatal milk expressing a randomised controlled trial ACTRN12611000217909 Mother & Child Health Research, La Trobe University d.foster@latrobe.edu.au Recruitment complete Diabetes