Trial Name Trial ID Main Coordinating Centre
and contact
Status Recruitment Topic Participants
Does telephone peer support and/or a midwife home visit in the early postnatal period increase breastfeeding duration? ISRCTN17386721 d.forster@latrobe.edu.au Discontinued Breastfeeding. Parental social and emotional wellbeing
CHOPP (Childhood Obesity Primary Prevention) Study - A pregnancy intervention to reduce postprandial glucose excursions in the primary prevention of paediatric obesity ISRCTN10344179 j.brandmiller@mmb.usyd.edu.au Discontinued
PINK - Pregnancy iodine and neurodevelopment in kids ACTRN12610000411044 jo.zhou@adelaide.edu.au Discontinued Iodine, pregnancy, child development Mothers and children
OPTIMIST-B - Multicentre randomised controlled trial of minimally-invastive surfactant therapy in preterm infants 29-32 weeks gestation on continuous positive airway pressure ACTRN12611000917932 Royal Hobart Hospital, Tas peter.dargaville@dhhs.tas.gov.au Discontinued Newborn respiratory
WILD B - Women and the Induction of Labour Dilemma-Trial B PT0520 Jocelyn Toohill Discontinued
MORP - A prospective comparison of early post-operative analgesia in Caesarean Section using bilateral ilio-inguinal block and sub-cutaneous morphine ACTRN12605000771651 Royal Women's Hospital, Vic Phil Popham Discontinued
Self-management versus usual care for the treatment of mastitis following childbirth: a randomised controlled trial ACTRN12607000438459 Maree Crepinsek Discontinued Breastfeeding
WIPPET - The effect of levobupivicaine Wound Infusion, for 24 hours, on Postoperative Pain after caEsarean secTion - a prospective, randomised, double-blind parallel-group placebo controlled clinical trial ACTRN12605000241639 Michael Paech Discontinued
Efficacy of ultrasound guided Transversus Abdominis Plane (TAP) block following major abdominal surgery (elective caesarean section): a randomised controlled trial ACTRN12607000389404 St Vincent Hospital michael.barrington@svhm.org.au Discontinued Labour and intrapartum care
McMOPS - McRoberts manoeuvre or pushing study NCT00116246 Sheila Mulvey Discontinued
Cooling for perineal pain relief after childbirth: randomised trial ACTRN12607000557437 University of Melbourne/Royal Women`s Hospital eastc@unimelb.edu.au Discontinued
MPG Trial - Metformin in the Prevention of Gestational Diabetes ACTRN12610000157077 Women`s and Children`s Hospital, Children`s Youth and Women`s Health Service, North Adelaide suzette.coat@adelaide.edu.au Discontinued Prevention of recurrent Gestational diabetes Women who have had a previous pregnancy affected by GDM
HINT Trial - High-flow nasal cannulae versus ambient oxygen for the treatment of newborn infants with early respiratory distress in non-tertiary special care nurseries: a multicentre, randomised controlled trial ACTRN12611000233921 Gosford Hospital and The Royal Women's, Melbourne abuckmaster@nsccahs.health.nsw.gov.au Discontinued Newborn respiratory
CureNeb - Aerosolized surfactant in the first hour of life ACTRN12610000857000 King Edward Memorial Hospital Dr Stefan Minocchieri/Prof J J Pillow Discontinued Newborn respiratory
Flows at Lower Rates (FLoRa) - Is bias gas flow in ventilated preterm babies related to lung injury and risk of bronchopulmonary dysplasia? ACTRN12611000628943 Liggins Institute, University of Auckland kittyb@adhb.govt.nz; f.bloomfield@auckland.ac.nz Discontinued Newborn respiratory Babies born at < 28 weeks’ or < 1,000 g needing ventilation in first week of life
A double-blind randomised controlled trial of oxytocin bolus plus placebo infusion versus oxytocin bolus plus oxytocin infusion at elective caesarean section ACTRN12607000631404 Monash Medical Centre joanne.mockler@med.monash.edu.au Discontinued Labour and intrapartum care Singleton pregnancy, gestation 37 - 41 weeks, elective lower segment caesarean section, regional anaesthesia (spinal, epidural, combined spinal epidural (CSE))
The ICE Pilot - Inadvertent dural puncture in labour: Intrathecal catheter versus epidural ACTRN12608000009314 allan Cyna Discontinued Labour and intrapartum care
e-prem - Improving child and parent outcomes after preterm birth using a web-based early intervention program ACTRN12614000906651 Murdoch Childrens Research Institute karli.treyvaud@mcri.edu.au Discontinued
Prediction of normal vaginal delivery PT0547 Nepean Hospital Hans Peter Dietz Discontinued
Improving oral hygiene to reduce the risk of preterm birth: A randomised controlled trial assessing a high intensity educational intervention ACTRN12605000767606 caroline.crowther@adelaide.edu.au Discontinued Preterm birth ? prevention and treatment Women with a singleton pregnancy
PINT study - Premature Infants In Need of Transfusion PTO387/NCT00182390 Chad Andersen Recruitment complete Babies with birth weight <1000g, postnatal age <48 hours, no transfusion beyond first 6 hours of life, estimated gestational age of 30 completed weeks or less
FOREMOST trial - Fetal intrapartum pulse oximetry: a multicentre randomised controlled trial PT0360/NHMRC301050/ACTRN012606000307505 Christine East Recruitment complete Labour and intrapartum care
BBB - Beating the Blues before Birth ACTRN12607000397415 Christopher Holt Recruitment complete Social and emotional wellbeing in pregnancy
Folic Acid Clinic Trial (FACT) - Effect of folic acid supplementation in pregnancy on pre-eclampsia ISRCTN23781770; NCT01355159 Ottawa Health Research Institute, Ottawa, Canada bill.hague@adelaide.edu.au Recruitment complete Preeclampsia
BBBi - Beating the Blues before Birth (individual treatment) ACTRN12609000926235 Parent-Infant Research Institute, Austin Health, (03) 9496 4496, piri@austin.org.au
Recruitment complete Antenatal depression, cognitive-behavioural therapy, treatment Participants are women aged 18 years or over who are less than 32 weeks pregnant and who meet the Diagnostic and Statistical Manual of Mental Disorders Fourth Edition (DSM-IV) diagnostic criteria for either Major Depression, Minor Depression, Adjustment Disorder with depressed mood, or Adjustment Disorder with mixed anxiety and depressed mood.
Trial Evaluation of the VAMP (Venous/Arterial Blood Management Protection) closed method of blood sampling from arterial umbilical catheters in very low birth-weight neonates. PT0358 David Tudehope Recruitment complete
HUGS - Early intervention to protect the mother-infant relationship following postnatal depression - a randomised controlled trial ACTRN12612001110875 Parent-Infant Research Institute, Austin Health, (03) 9496 4496, piri@austin.org.au
Recruitment complete Postnatal depression, mother-infant interaction Women aged 18 years or older with an infant aged 3-9 months and a clinical diagnosis of current major or minor depressive episode
SMILE Study - Prevention of preterm birth by treatment of periodontal disease during pregnancy NCT00133926/NHMRC353577 ddoherty@obsgyn.uwa.edu.au Recruitment complete Preterm birth ? prevention and treatment
MMB: MumMoodBooster - Web-based cognitive behavioural therapy for women with postnatal depression ACTRN12613000113752 Parent-Infant Research Institute, Heidelberg Repatriation Hospital VIC jeannette.milgrom@austin.org.au Recruitment complete
FRUIT-Study - Low-molecular-weight heparin added to aspirin in the prevention of recurrent early-onset pre-eclampsia in women with inheritable thrombophilia ISRCTN87325378 Department of Obstetrics and Gynaecology, VU University Medical Center, Amsterdam,
Netherlands.
Prof JIP de Vries (Chief Investigator) jip.devries@vumc.nl
Recruitment complete Preeclampsia. Fetal growth. Maternal medical conditions women with previous pregnancy with hypertensive disease and/or SGA <34 weeks and an inheritable thrombophilia
Help-seeking for postnatal depression as a major public health problem: A cluster randomised controlled trial of motivational interviewing ACTRN12611000635965 Parent-Infant Research Institute, Austin Health, (03) 9496 4496, piri@austin.org.au
Recruitment complete Motivational interviewing, postnatal depression Women with a 4-week old baby
PRIVA Trial - A comparison of the overall pain scores post caesarean section, when initial intraoperative analgesia is given intravenously (IV) versus per rectum (PR) ACTRN12614001144606 dlowen@gmp.usyd.edu.au Recruitment complete
PERUSAL - Pre-Epidural Rapid UltraSound assessment of Anatomical Landmarks in obese parturients ACTRN12610000228088 Dr Chris Mitchell Recruitment complete
Effect of position during bottle feeding on physiological stability in preterm infants ACTRN12611000944932 Dr Jennifer Dawson Recruitment complete Newborn nutrition
The efficacy and feasibility of progressive strength training in the management of glucose control in women with gestational diabetes ACTRN12605000378628 Elena Vulikh Recruitment complete Diabetes
Omega-3 fatty acids as a treatment for perinatal depression: randomized double-blind placebo-controlled trial Prince Alfred Hospital/University of New South Wales Recruitment complete Social and emotional wellbeing in pregnancy
HFNP WHO RCT - Pilot randomised control trial of high-flow nasal prong warm, humidified oxygen (HFNP WHO) compared to standard oxygen therapy ACTRN12612000685819 Elizabeth.Kepreotes@hnehealth.nsw.gov.au Recruitment complete
Efficacy and safety of a novel fish oil based lipid emulsion (SMOFlipid) compared with olive oil based lipid emulsion (Clinoneic) in term and near-term (>34 weeks) neonates - a randomised controlled trial ACTRN12609000337279 Princess Margaret Hospital for Children, WA girish.deshpande@health.wa.gov.au Recruitment complete Newborn nutrition
The effect of intrathecal pethidine on shivering in women having caesarean sections: a prospective randomised controlled trial ACTRN12605000065695 Gabe Snyder Recruitment complete
IFOS - The Infant Fish Oil Supplementation Study ACTRN12606000281594 Princess Margaret Hospital
S J Meldrum
Recruitment complete Newborn nutrition
A pilot randomised control trial on maternal antenatal teaching for pushing in second stage of labour PUSH Study ACTRN12608000542392 hala.phipps@sswahs.nsw.gov.au Recruitment complete Labour and intrapartum care
QuEST Trial - Questioning the role of egg in lactation for induction of specific tolerance ACTRN12613000643774 Princess Margaret Hospital, Subiaco, WA debbie.palmer@uwa.edu.au Recruitment complete Allergens and epitopes, clinical immunology, food allergy, pediatrics, prevention
POPOUT Study - Persistent Occipito-Posterior: Outcomes following digital rotation. ACTRN12609000833268 hala.phipps@sswahs.nsw.gov.au Recruitment complete
Probiotic Allergy Prevention Study ACTRN12606000280505 Princess Margaret Hospital, WA Susan Prescott Recruitment complete
Shift your Risk - The feasibility and efficacy of an individualised approach to increase physical activity among women with previous gestational diabetes mellitus. ACTRN12608000280303 HD McIntyre Recruitment complete
Hydrocortisone Trial Early adrenal insufficiency in very premature infants PT0364 Helen Liley Recruitment complete
Brief antenatal cognitive behaviour therapy group intervention for the prevention of postnatal depression and anxiety: a randomised controlled trial RHW, Sydney Recruitment complete Parental social and emotional wellbeing
UACC study - Umbilical Arterial Catheterisation Calculation Study PT0398 I M R Wright Recruitment complete
Getting Research into practice - a randomised controlled trial of an educational intervention aimed at increasing the uptake of evidence based guidelines for term prom and for early onset GBS disease J King Recruitment complete
CUT Trial - A prospective, randomised study Comparing cUrved versus straighT scissors to reduce episiotomy extension ACTRN12612000285853 Royal Brisbane & Women's Hospital angela_swift@health.qld.gov.au Recruitment complete Labour and intrapartum care