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Trial Name Trial ID Main Coordinating Centre
and contact		 Status Recruitment Topic Participants Details
NIP Study - Neonatal Inhaled Pentoxifylline for early and delayed treatment of chronic lung disease PTO389 John Sinn Suspended
Novel feeding system to promote the establishment of breastfeeding after preterm birth a randomised controlled trial ACTRN12614000875606 University of Western Australia karen.simmer@health.wa.gov.au Recruitment complete
Omega-3 fatty acids as a treatment for perinatal depression: randomized double-blind placebo-controlled trial Prince Alfred Hospital/University of New South Wales Recruitment complete Social and emotional wellbeing in pregnancy
Open versus specific questioning to assess pain during anaesthetic follow-up after caesarean birth: a randomised trial ACTRN12609000121268 Women's & Children's Hospital Allan Cyna Recruitment complete Labour and intrapartum care Women within 72 hour of their caesarean section
OPIO - Optimising preterm infant outcomes: a RCT to evaluate two screening & surveillance methods PT0518/ACTRN012606000472572 Margo Pritchard Recruitment complete Newborn ? developmental
OPRA - Outpatient cervical priming for induction of labour ACTRN12608000249358 Women's and Children's Hospital chrisswilkinson@mac.com Recruitment complete Models of care. Labour and intrapartum care Pregnant women having priming for induction of labour, where induction is clinically indicated, there is no evidence of maternal or fetal compromise and in the opinion of the referring caregiver, outpatient management and monitoring is clinically appropriate
Optimisation of the management of placental delivery in second trimester pregnancy interruption NCT00120042 King Edward Memorial Hospital, WA Jan Dickinson Recruitment complete
OPTIMIST-B - Multicentre randomised controlled trial of minimally-invastive surfactant therapy in preterm infants 29-32 weeks gestation on continuous positive airway pressure ACTRN12611000917932 Royal Hobart Hospital, Tas peter.dargaville@dhhs.tas.gov.au Discontinued Newborn respiratory
Oral misoprostol versus intravenous oxytocin for induction of labour following artificial or spontaneous rupture of membranes jodie.dodd@adelaide.edu.au Recruitment complete Labour and intrapartum care Women > or = 41 weeks booked for delivery at Women's and Children's Hospital; singleton pregnancy; cephalic presentation
OSCAR - Women undergoing combined spinal epidural for elective caesarean section, ondansetron 8mg versus placebo to prevent perioperative shivering ACTRN12609000445279 Fremantle Hospital roger.browning@health.wa.gov.au Recruitment complete Labour and intrapartum care
Pain versus comfort scores after caesarean section: a randomised trial ACTRN12610000890033 Department of Women's Anaesthesia, Women's & Children's Hospital Allan Cyna Recruitment complete Labour and intrapartum care All English speaking women who are scheduled for post-anaesthesia review following caesarean section.
PANTS - A randomised placebo controlled pilot trial on the safety and efficacy of a probiotic product in reducing all case mortality and definite necrotizing enterocolitis in preterm very low birthweight neonates ACTRN12609000374268 sanjay.patole@health.wa.gov.au Recruitment complete
PDA Trial - Paracetamol Duct Action: The effect of paracetamol vs placebo on ductal closure in premature infants with a late patent ductus arterious ACTRN12611000741987 Royal North Shore Hospital, NSW Prof Martin Kluckow martin.kluckow.usyd.edu.au Recruitment complete PDA closure, Preterm infant, Paracetamol Population: Preterm infants born <33 weeks gestational age with a persistent PDA who are >4 weeks of postnatal age and tolerating at least 50% enteral feeds.
Perinatal treatment of depression ACTRN12609000831280 Royal Brisbane Hospital Sally Matherson Suspended Parental social and emotional wellbeing
Perineal outcomes and maternal comfort related to the application of perineal warm packs in the second stage of labor: a randomised controlled trial Royal Prince Alfred Women and Babies, NSW Recruitment complete Labour and intrapartum care
PERUSAL - Pre-Epidural Rapid UltraSound assessment of Anatomical Landmarks in obese parturients ACTRN12610000228088 Dr Chris Mitchell Recruitment complete
Phototherapy and Patency of the Ductus Arteriosus in Extremely Preterm infants: A randomised Trial Karen Simmer Recruitment complete
PICOP - Use of chlorhexidine as a topical antiseptic for the prevention of nosocomial infection in premature neonates < 29 weeks: a blinded randomised controlled trial RPA Women's and Babies sandie@email.cs.nsw.gov.au Recruitment complete
PIFI - Parent Infant Feeding Initiative: a study to enhance breastfeeding duration ACTRN12614000605695 Curtin University, Perth, Western Australia. Prof Jane Scott jane.scott@curtin.edu.au Recruitment complete Health promotion/education; Breastfeeding Expectant couples (mothers and fathers)
PINK - Pregnancy iodine and neurodevelopment in kids ACTRN12610000411044 jo.zhou@adelaide.edu.au Discontinued Iodine, pregnancy, child development Mothers and children
PINT study - Premature Infants In Need of Transfusion PTO387/NCT00182390 Chad Andersen Recruitment complete Babies with birth weight <1000g, postnatal age <48 hours, no transfusion beyond first 6 hours of life, estimated gestational age of 30 completed weeks or less
PIVOT - Parenteral intravenous optimal treatment for hypertensive emergencies in pregnancy PTO388 Annemarie Hennessy Recruitment complete
PLUTO - Percutaneous shunting for lower urinary tract obstruction ISRCTN53328556 The Clinical Trials Unit, University of Birmingham. Professor Mark Kilby (Chief Investigator) m.d.kilby@bham.ac.uk Recruitment complete Fetal anomaly women with pregnancy with a male fetus complicated by isolated lower urinary tract obstruction (LUTO)
PneuMum - Pneumococcal Vaccination of Australian Indigenous Mothers to See if it Protects their babies from Ear Disease NCT00310349; NCT00714064 Menzies School of Health Research Amanda Leach Recruitment complete
POINT - Safety and efficacy of pentoxifylline as a treatment for preventing the progression of necrotising enterocolitis in preterm neonates - A randomised placebo controlled pilot trial ACTRN12606000257561 sanjay.patole@health.wa.gov.au Recruitment complete
POP-OUT - Persistent Occiput Posterior: OUTcomes following manual rotation ACTRN12612001312831 Royal Prince Alfred Hospital, NSW hala.phipps@email.cs.nsw.gov.au Recruitment complete
IMPACT reviewed
 Labour and intrapartum care
POPOUT Study - Persistent Occipito-Posterior: Outcomes following digital rotation. ACTRN12609000833268 hala.phipps@sswahs.nsw.gov.au Recruitment complete
POPPET - Providing Optimal Protein for Prems via Enteral Tubes. Does increasing the protein content of human milk fortifier improve growth in preterm infants <33 weeks gestation? A randomised controlled trial. ACTRN12611001275954 Women's & Children's Health Research Institute jessica.reid@adelaide.edu.au Recruitment complete Newborn nutrition Infants <33 completed weeks gestation whose mothers intend to provide breast milk
Positioning to improve lung function in preterm infants requiring ventilatory support ACTRN12606000210572 judith.hough@mater.org.au Recruitment complete
Postnatal Perineal Pain Project ACTRN12609000555257 Kristen Rickard Recruitment complete
PPBCR - Parental presence on bedside clinical rounds (PPBCR) in a neonatal intensive care unit (NICU) ACTRN12612000506897 Department of Neonatology, The Canberra Hospital Margaret Broom Recruitment complete
PPROMT - Immediate delivery vs expectant care in women with preterm prelabour rupture of the membranes close to term - A randomised clinical trial PT0536/ISRCTN44485060/NHMRC358378 Dept of Obstetrics & Gynaecology, Royal North Shore Hospital ppromt@med.usyd.edu.au Recruitment complete Preterm birth ? improving outcomes (antenatal interventions) Singleton pregnancies, with confirmed ruptured membranes from 34 weeks to 36 weeks and 6 days gestation.
PRAM - Prospective Randomised Automated versus Mercury blood pressure recordings in hypertensive pregnancy NCT00809666 University of Sydney Lynne Roberts Recruitment complete Maternal medical conditions
pre-hPOD - Hypoglycaemia prevention in newborns with oral dextrose ACTRN12613000322730 Liggins Insitute, University of Auckland Dr Jo Hegarty: j.hegarty@auckland.ac.nz Recruitment complete
Prediction of normal vaginal delivery PT0547 Nepean Hospital Hans Peter Dietz Discontinued
PREGGIO - Pregnancy and Glycaemic Index Outcomes Study comparing a low glycaemic index (GI) diet to a standard healthy diet ACTRN12610000174088 Clinical Trials & Research Unit South East Sydney & Illwarra Area Health Service Diabetes Centre Shelly Charters Recruitment complete Maternal nutrition
PremieStart - Improving neurobehavioural development in preterm infants ACTRN12606000412538 Austin Health, Vic Jeannette Milgrom Recruitment complete
Prevention of hypothermia in the delivery room for preterm infants <30 weeks gestation ACTRN12608000212358 Department of Neonatology, Townsville Hospital, QLD jacquelineJ_smith@health.qld.gov.au Recruitment complete
Prevention of low systemic blood flow and brain injury in very preterm babies using Milrinone PT0390 Nick Evans Recruitment complete
Prevention of Overweight in Infancy (POI.nz) study: a randomised controlled trial of sleep, food and activity interventions for preventing overweight from birth NCT00892983 University of Otago Barry J Taylor Recruitment complete
PRIME - The effect of midwife-led counselling on mental health outcomes for women experiencing a traumatic childbirth: a randomised controlled trial ACTRN12610000098033 j.gamble@griffith.edu.au Recruitment complete Parental social and emotional wellbeing
PRISM - Program of Resources, Information and Support for Mothers ISRCTN03464021; NHMRC191215; PT0523 La Trobe University (Australia): Prof Judith Lumley Recruitment complete
PRIVA Trial - A comparison of the overall pain scores post caesarean section, when initial intraoperative analgesia is given intravenously (IV) versus per rectum (PR) ACTRN12614001144606 dlowen@gmp.usyd.edu.au Recruitment complete
Probiotic Allergy Prevention Study ACTRN12606000280505 Princess Margaret Hospital, WA Susan Prescott Recruitment complete
Probiotic Eczema Prevention Study (CSG Trial No. 36) Dept of Immunology, Royal Children's Hospital, Vic Robert Boyle Recruitment complete
PROGRESS - Australian Collaborative trial of vaginal progesterone for prevention of neonatal respiratory distress syndrome ISRCTN20269066; NHMRC399137 Maternal Perinatal Clinical Trials Unit, Adelaide Women's and Children's Pat Ashwood Recruitment complete Preterm birth ? prevention and treatment. Preterm birth ? improving outcomes (antenatal interventions). Newborn respiratory Pregnant women with a history of prior spontaneous preterm birth at less than 34 weeks gestation
ProPrem - The use of probiotics to reduce the incidence of sepsis in premature infants ACTRN12607000144415 Royal Women's Hospital Linh Ung Recruitment complete Newborn infection. Newborn nutrition
Protein in Preterm Infant Nutrition ACTRN12606000525583 Jacqueline Miller Recruitment complete
QuEST Trial - Questioning the role of egg in lactation for induction of specific tolerance ACTRN12613000643774 Princess Margaret Hospital, Subiaco, WA debbie.palmer@uwa.edu.au Recruitment complete Allergens and epitopes, clinical immunology, food allergy, pediatrics, prevention
Randomised control trial comparing the use of the Neobar endotracheal tube holder with standard taping technique for nasal intubation in the newborn infant Kristen James Recruitment complete Newborn cardiovascular