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Trial Name Trial ID Main Coordinating Centre
and contact		 Status Recruitment Topic Participants Details
VITAL Trial - The effects of vitamin D supplementation in infancy on immune development ACTRN12612000787886 Childhood Allergy and Immunology Research, University of Western Australia, Dr Debbie Palmer, Ph: + 61 410 851 607, debbie.palmer@uwa.edu.au
 Recruitment complete Vitamin D, infants, immune development Infants with a family history of allergic disease
Selenium status of term infants fed selenium-supplemented formula in a randomized dose-response trial Maria Makrides Recruitment complete Newborn nutrition
DETECT - Targeting of treatment of the patent ductus arteriosus using early echocardiography ACTRN12608000295347 martin.kluckow@sydney.edu.au Recruitment complete Newborn cardiovascular
Furosemide for packed red cell transfusion in preterm infants: a randomized controlled trial martin.kluckow@sydney.edu.au Recruitment complete
A randomised controlled trial of Baby Triple P: an evaluation of an antenatal parenting program to improve parental responsiveness in first-time parents ACTRN12613000948796 School of Psychology, University of Queensland mandy.mihelic@uq.net.au Recruitment complete
SILC - Supporting breastfeeding In Local Communities ACTRN12611000898954 Meabh Cullinane Recruitment complete Breastfeeding
MEDSTORM - The use of skin conductance monitoring to predict severe hypotension after spinal anaesthesia for elective caesarean section Michael Paech Recruitment complete
The Motherhood Choices Decision Aid for Women with Rheumatoid Arthritis Increases Knowledge and Reduces Decisional Conflict: A Randomized Controlled Study ACTRN12615000523505 School of Social Science and Psychology, University of Western Sydney t.meade@uws.edu.au Recruitment complete
WIPPET - The effect of levobupivicaine Wound Infusion, for 24 hours, on Postoperative Pain after caEsarean secTion - a prospective, randomised, double-blind parallel-group placebo controlled clinical trial ACTRN12605000241639 Michael Paech Discontinued
Magnesium Sulfate for pain relief after Caesarean birth Michael Paech Recruitment complete Labour and intrapartum care
Can a low-glycemic index diet reduce the need for insulin in gestational diabetes mellitus South Eastern Sydney and Illawarra Area Health Service robert.moses@sesiahs.health.nsw.gov.au Recruitment complete Diabetes. Maternal nutrition
A Randomised Double Blind Crossover Trial of Intranasal Versus Epidural Fentanyl Patient Controlled Analgesia for Pain Relief after Caesarean Section ACTRN12605000327684 michael.paech@health.wa.gov.au Suspended
Effect of humidified and non humidified T piece resuscitation on admission temperatures in preterm infants <32 weeks: a randomised controlled trial ACTRN12609000694213 mmeyer@middlemore.co.nz Recruitment complete
Efficacy of ultrasound guided Transversus Abdominis Plane (TAP) block following major abdominal surgery (elective caesarean section): a randomised controlled trial ACTRN12607000389404 St Vincent Hospital michael.barrington@svhm.org.au Discontinued Labour and intrapartum care
Evaluation of a Decision Aid for women with a breech-presenting baby PT0512/ISRCTN14570598/NHMRC211051&262041 Natasha Nassar Recruitment complete
TRIGR - Primary Prevention Study for Type 1 Diabetes in Children at Risk NCT00179777 Neville Howard Recruitment complete
Does early whooping cough (pertussis) vaccination provide earlier antibody protection for infants? A pilot study to determine the appropriate design for a trial of acellular pertussis vaccine given at birth? ACTRN12605000013662 Nicholas Wood Recruitment complete
A randomised controlled trial comparing daily (400 IU) and single bolus dosing (50,000 IU) of vitamin D in healthy breastfed infants of vitamin D deficient mothers ACTRN12613001234707 Sunshine Hospital
julie.huynh@wh.org.au; christine.rodda@unimelb.edu.au		 Recruitment complete
Prevention of low systemic blood flow and brain injury in very preterm babies using Milrinone PT0390 Nick Evans Recruitment complete
Randomised trial of dopamine vs dobutamine for treatment of low systemic blood flow in very preterm infants ACTRN12607000152426 Nick Evans Recruitment complete Newborn cardiovascular
TIPP - Trial of indomethacin prophylaxis in preterms NCT00009646 Peter Davis Recruitment complete
MIOH-DS pilot - Piloting of a Midwife Initiated Oral Health-Dental Service (MIOH-DS) to improve the oral health of pregnant women ACTRN12610000794000 Sydney South West Area Health Service/University of Western Sydney Dr Ajesh George Recruitment complete
CAP Trial - Caffeine for Apnea of Prematurity Trial PT0357 Peter Davis Recruitment complete Newborn respiratory
Effect of the 'Mother and Baby' program on new mothers' psychological and physical well-being NCT00361478 The Angliss Hospital, Vic Recruitment complete Parental social and emotional wellbeing
Examining the effectiveness of a creative-arts therapy, antenatal intervention program in comparison with an informal ante-natal birth support group for first-time mothers, on reducing levels of depression, anxiety and the use of analgesics during labour ACTRN12606000051549 Primrose White Recruitment complete
Continuous positive airway pressure (CPAP) weaning trial ACTRN12606000155594 The Canberra Hospital, ACT Chetan Pandit Recruitment complete
Randomised double cross over study of assisted control ventilation (A/C) versus intermittent ventilation (IMV) in preterm babies weaning off ventilation PT0366 R Lau Recruitment complete
PLUTO - Percutaneous shunting for lower urinary tract obstruction ISRCTN53328556 The Clinical Trials Unit, University of Birmingham. Professor Mark Kilby (Chief Investigator) m.d.kilby@bham.ac.uk Recruitment complete Fetal anomaly women with pregnancy with a male fetus complicated by isolated lower urinary tract obstruction (LUTO)
A group randomised trial of two methods for disseminating a smoking cessation programme to public antenatal clinics: effects on patient outcomes Raoul Walsh Recruitment complete
Midwife-led debriefing after operative birth: four to six year follow-up of a randomised trial Rhonda Small Recruitment complete
right@home: A national sustained nurse home visiting trial to promote family wellbeing and child development ISRCTN89962120 Dr Anna Price, Centre for Community Child Heath, The Royal Children’s Hospital
Flemington Road, Parkville Vic 3052, anna.price@mcri.edu.au		 Recruitment complete Child development, Home visits, Social adversity Australian women who were less than 37 weeks gestation, had sufficient English proficiency to verbally answer interview questions, disclosed two or more of 10 risk factors identified by screening, and had home addresses within travel boundaries specified by the participating councils/regions
POINT - Safety and efficacy of pentoxifylline as a treatment for preventing the progression of necrotising enterocolitis in preterm neonates - A randomised placebo controlled pilot trial ACTRN12606000257561 sanjay.patole@health.wa.gov.au Recruitment complete
PANTS - A randomised placebo controlled pilot trial on the safety and efficacy of a probiotic product in reducing all case mortality and definite necrotizing enterocolitis in preterm very low birthweight neonates ACTRN12609000374268 sanjay.patole@health.wa.gov.au Recruitment complete
McMOPS - McRoberts manoeuvre or pushing study NCT00116246 Sheila Mulvey Discontinued
TRiM - Trial for Reducing Weight Retention in New Mums: a randomised controlled trial investigating the effectiveness of an innovative postpartum weight loss program in new mothers ACTRN12611000873921 shelley.wilkinson@mater.org.au Recruitment complete
MBB - A pilot study to test recruitment methods, feasibility and study procedures for a planned randomised controlled trial of the MindBabyBody program: an antenatal mindfulness intervention to reduce depression, stress and anxiety ACTRN12613000742774 The Royal Women's Hospital, Parkville, Vic hannah.woolhouse@mcri.edu.au Recruitment complete
A double blind randomised controlled trial of Domperidone and Metoclopramide as pro-lactational agents in mothers of preterm infants PT0392 simon.james@flinders.edu.au Recruitment complete Breastfeeding
HIPSTER Trial - High Flow Nasal Cannulae as Primary Support in the Treatment of Early Respiratory Distress ACTRN12613000303741 The Royal Women's Hospital, Vic calum.roberts@thewomens.org.au Recruitment complete
Nasal versus face mask for multiple-breath washout technique in preterm infants SM Schulzke Recruitment complete
WIP - Weighing In Pregnancy ACTRN12610000331033 The Royal Women's Hospital, Vic Fiona Brownfoot Recruitment complete
A postnatal support program and its effect on breastfeeding duration PT0379 Sue McDonald Recruitment complete
A preventative intervention for illicit drug using mothers and their infants Sue McDonald Recruitment complete
Effects of probiotics on atopic dermatitis: a randomised controlled trial Susan Prescott Recruitment complete
A comparison of axillary and tympanic temperature recording in the preterm and term infant ACTRN12608000213347 The Townsville Hospital, Qld
Jacqueline Smith		 Recruitment complete
Improving the outcome of premature infants - a randomised trial of preventive care at home NHMRC284512 Terrie Inder Recruitment complete
A*STEROID - Australasian Antenatal Study to Evaluate the Role Of Intramuscular Dexamethasone versus betamethasone prior to preterm birth to increase survival free of childhood neurosensory disability - a randomised controlled trial ACTRN12608000631303 The University of Adelaide / Women's & Children's Hospital pat.ashwood@adelaide.edu.au Recruitment complete Preterm birth ? improving outcomes (antenatal interventions). Newborn respiratory Women at risk of preterm birth at less than 34 weeks gestation, have a singleton or twin pregnancy and no contraindications to the use of antenatal corticosteroids
HOPE Trial - Prevention of recurrent pre-eclampsia by folic acid and supplementation in women with hyperhomocysteinaemia PT0362 William Hague Recruitment complete Preeclampsia
Effects of different levels of incubator humidity on temperature and fluid and electrolyte balance in infants born at 28 weeks and less ACTRN12606000138583 Yuk-Shan Kong Recruitment complete
Fetal Middle Cerebral Artery Doppler (MCA) velocimetry to determine the timing of second and subsequent fetal blood transfusions in the treatment of fetal anaemia secondary to red cell alloimmunisation - a randomised controlled trial ACTRN12608000643370 The University of Adelaide, SA jodie.dodd@adelaide.edu.au Recruitment complete Fetal surveillance Pregnant women whose fetus has anaemia secondary to red cell alloimmunisation (due to any red cell antibody alone or in combination) as indicated by the need to have performed a single intra-uterine fetal blood transfusion
ACTOMgSO4 - Australasian Collaborative Trial of Magnesium Sulphate for the Prevention of Mortality and Cerebral Palsy in Infants Born Very Preterm PT0354/ACTRN012606000252516 Adelaide Women's and Children's caroline.crowther@adelaide.edu.au Recruitment complete Preterm birth ? improving outcomes (antenatal interventions) Pregnant women of gestation less than 30 weeks where delivery is planned or definately expected within 24 hours