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Trial Name Trial ID Main Coordinating Centre
and contact		 Status Recruitment Topic Participants Details
PPROMT - Immediate delivery vs expectant care in women with preterm prelabour rupture of the membranes close to term - A randomised clinical trial PT0536/ISRCTN44485060/NHMRC358378 Dept of Obstetrics & Gynaecology, Royal North Shore Hospital ppromt@med.usyd.edu.au Recruitment complete Preterm birth ? improving outcomes (antenatal interventions) Singleton pregnancies, with confirmed ruptured membranes from 34 weeks to 36 weeks and 6 days gestation.
CLOSURE - Skin and subcutaneous fascia closure at caesarean section: a randomised controlled trial ACTRN12608000143325 Discipline of Obstetrics and Gynaecology, Women's and Children's Hospital rosalie.grivell@adelaide.edu.au Recruitment complete Labour and intrapartum care Women undergoing a caesarean section by transverse suprapubic incision
right@home: A national sustained nurse home visiting trial to promote family wellbeing and child development ISRCTN89962120 Dr Anna Price, Centre for Community Child Heath, The Royal Children’s Hospital
Flemington Road, Parkville Vic 3052, anna.price@mcri.edu.au		 Recruitment complete Child development, Home visits, Social adversity Australian women who were less than 37 weeks gestation, had sufficient English proficiency to verbally answer interview questions, disclosed two or more of 10 risk factors identified by screening, and had home addresses within travel boundaries specified by the participating councils/regions
txt4two - Testing the feasibility of an intervention program to promote healthy nutrition, physical activity and weight gain in pregnant women ACTRN12614000288628 Dr Jane Wilcox, School of Exercise and Nutrition Sciences, Deakin University jwillcox@deakin.edu.au Recruitment complete Gestational weight gain, mHealth, nutrition
 Eligible women were identified at their first hospital antenatal visit to a university-affiliated maternity hospital in Melbourne, Australia. Eligibility criteria included women with a singleton, live gestation between 10+0-17+6 weeks; self-reported pre-pregnancy BMI>25kg/m2; able to speak, read and write English; and owned a mobile phone.
A comparison of fentanyl with pethidine for pain relief during childbirth ACTRN126090001027202 Flinders University/Flinders Medical Centre
Julie Fleet		 Recruitment complete Labour and intrapartum care
The effects of health related bio-markers in healthy women of child-bearing age consuming a diet higher in fish when compared to those who consumed a typical Australian diet higher in meat ACTRN12610000572066 Flinders Univesity lily.chan@flinders.edu.au Recruitment complete
OSCAR - Women undergoing combined spinal epidural for elective caesarean section, ondansetron 8mg versus placebo to prevent perioperative shivering ACTRN12609000445279 Fremantle Hospital roger.browning@health.wa.gov.au Recruitment complete Labour and intrapartum care
HINT Trial - High-flow nasal cannulae versus ambient oxygen for the treatment of newborn infants with early respiratory distress in non-tertiary special care nurseries: a multicentre, randomised controlled trial ACTRN12611000233921 Gosford Hospital and The Royal Women's, Melbourne abuckmaster@nsccahs.health.nsw.gov.au Discontinued Newborn respiratory
DRESSING Trial - ADding negative pRESSure to improve healING in obese women undergoing caesarean section - PILOT ACTRN12612000171819 Griffith University w.chaboyer@griffith.edu.au Recruitment complete Labour and intrapartum care. Obesity
A pilot randomised control trial on maternal antenatal teaching for pushing in second stage of labour PUSH Study ACTRN12608000542392 hala.phipps@sswahs.nsw.gov.au Recruitment complete Labour and intrapartum care
Toward Parenthood: delivering an antenatal self-help intervention with telephone support for depression, anxiety and parenting difficulties - facilitating the perinatal health journey ACTRN12606000263594 Heidelberg Repatriation Hospital, Vic Jennifer Ericksen Recruitment complete
MAP study - Managing asthma in Pregnancy ACTRN12607000561482 Hunter Hospital Recruitment complete
A randomised controlled trial of a brief multi strategic child health nurse intervention to reduce infant secondhand smoke exposure ACTRN12614001032640 Hunter New England Health justine.daly@hnehealth.nsw.gov.au Recruitment complete
A randomised controlled trial comparing immediate and controlled release oxycodone the day after caesarean section ACTRN12613000076774 Ipswich Hospital, QLD Anthony_Schoenwald@health.qld.gov.au Recruitment complete
Bovine lactoferrin supplementation for prevention of necrotizing enterocolitis in very-low-birth-weight neonates: a randomized clinical trial ISRCTN53107700 Italy Michael Meyer Recruitment complete
HeLP for Mums - A community based low intensity lifestyle intervention to prevent weight gain in women with children ACTRN12608000110381 Jean Hailes Foundation for Women Health/ Monash University catherine.lombard@monash.edu Recruitment complete
HeLP-her - Healthier lifestyles: Preventing excess weight gain and gestational diabetes in overweight and obese pregnancies: a research and education project ACTRN12608000233325 Jean Hailes Research Group for Womens Health and Monash Institute of Health Services Research (Southern Health)MIMR Recruitment complete Obesity. Diabetes
A randomised controlled trial of dark chocolate in pregnancy for reduction in incidence of pre-eclampsia ISRCTN41164968 John James Medical Centre, Australian National University
stephen.robson@anu.edu.au		 Recruitment complete Preeclampsia
A comparison of Propofol and Suxamethonium as induction agents for neonatal endotracheal intubation PT0545 Julee Oei Recruitment complete Newborn respiratory. Newborn resuscitation
A double blind randomised controlled trial comparing the efficacy and safety of an olive oil based lipid emulsion (Clinoleic) to a soybean oil based lipid emulsion (Intralipid) in very preterm infants requiring parenteral nutrition Karen Simmer Recruitment complete
Balloon Trial - Caesarean section following induction of labour in nulliparous women with an unfavourable cervix: a comparison of three ripening agents - PGE2 Gel, single or double balloon catheter. ACTRN12609000186257 King Edward Memorial Hospital craig.pennell@uwa.edu.au Recruitment complete Labour and intrapartum care
CureNeb - Aerosolized surfactant in the first hour of life ACTRN12610000857000 King Edward Memorial Hospital Dr Stefan Minocchieri/Prof J J Pillow Discontinued Newborn respiratory
COMMAND Trial - Parecoxib, celecoxib and paracetamol for pain management following caesarean delivery. ACTRN12609001041246 King Edward Memorial Hospital for Women michael.paech@health.wa.gov.au Recruitment complete Labour and intrapartum care
The use of acupressure wristbands to prevent nausea and vomiting in labour and delivery ACTRN12607000585426 King Edward Memorial Hospital for Women, Perth Michael Paech Recruitment complete Labour and intrapartum care
Efficacy and safety of a new fish oil based lipid emulsion (SMOFlipid) compared with olive oil based lipid emulsion (Clinoleic) in preterm (<30 weeks) neonates - a randomised controlled trial ACTRN12609001017213 King Edward Memorial Hospital for Women, WA drgirishdeshpande@gmail.com Recruitment complete
SMOOTH - Oral analgesia compared with intrathecal morphine for pain after caesarean delivery: a randomised controlled trial ACTRN12606000506594 King Edward Memorial Hospital Michael Paech Recruitment complete
A randomised clinical trial at the time of spinal anaesthesia for elective caesarean section to investigate the effect of equipotent phenylephrine and metaraminol infusions on neonatal outcome ACTRN12612000996864 King Edward Memorial Hospital michael.paech@health.wa.gov.au Recruitment complete
Comparison of the EpiSure Autodetect syringe with the Portex loss-of-resistance syringe: a randomised controlled trial ACTRN12609000041257 King Edward Memorial Hospital, WA Suspended
Optimisation of the management of placental delivery in second trimester pregnancy interruption NCT00120042 King Edward Memorial Hospital, WA Jan Dickinson Recruitment complete
PRISM - Program of Resources, Information and Support for Mothers ISRCTN03464021; NHMRC191215; PT0523 La Trobe University (Australia): Prof Judith Lumley Recruitment complete
A prospective randomised trial to study the effect of intravenous iron therapy versus the standard treatment with oral iron for women diagnosed with iron deficiency anaemia in pregnancy ACTRN12609000177257 Launceston General Hospital
joanne.bates@dhhs.tas.gov.au		 Recruitment complete Maternal nutrition At risk women - dark skinned, veiled, Anyone with vitamin D deficiency that has not commenced treatment prior to recruitment
pre-hPOD - Hypoglycaemia prevention in newborns with oral dextrose ACTRN12613000322730 Liggins Insitute, University of Auckland Dr Jo Hegarty: j.hegarty@auckland.ac.nz Recruitment complete
IMPROVE - Improving Maternal and Progency Obesity Via Exercise: Antenatal exercise in overweight and obese women and its effects on offspring and maternal health ACTRN12612000932864 Liggins institute, The University of Auckland p.hofman@auckland.ac.nz Recruitment complete
Flows at Lower Rates (FLoRa) - Is bias gas flow in ventilated preterm babies related to lung injury and risk of bronchopulmonary dysplasia? ACTRN12611000628943 Liggins Institute, University of Auckland kittyb@adhb.govt.nz; f.bloomfield@auckland.ac.nz Discontinued Newborn respiratory Babies born at < 28 weeks’ or < 1,000 g needing ventilation in first week of life
The Healthy Start to Pregnancy study - an evaluation of a new early antenatal health promotion model of care for improving maternal health behaviours ACTRN12611000867998 Mater Medical Research Institute Dr Shelley Wilkinson Recruitment complete Social and emotional wellbeing in pregnancy
Ultrasound guided transverses abdominis plane (TAP) block for analgesia after caesarean surgery ACTRN12608000540314 Mater Misericordiae Health Services Brisbane Ltd Phillip Cowlishaw Recruitment complete
WILD A - Women and the Induction of Labour Dilemma-Trial A PT0519 Mater Mothers Hospital, Brisbane Paul Devenish-Meares Recruitment complete
SWITCh - A randomised, controlled trial of a single versus a four intradermal Sterile Water Injection Technique for relief of Continuous lower back pain during labour ACTRN12609000964213 Mater Mothers' Hospital nigel.lee@mater.org.au Recruitment complete Labour and intrapartum care
LOS trial - Prevention of late onset septicemia in infants in the neonatal intensive care unit, Mater Mothers' Hospital. PT0363 Mater Mothers' Hospital, Brisbane Helen Liley Recruitment complete Newborn infection
The prophylactic use of a Bakri balloon for women undergoing caesarean section for placenta praevia - a randomised controlled trial Bakri ACTRN12613000348752 Mater Mothers' Research Centre/Mater Health Services Michael Beckmann Recruitment complete Labour and intrapartum care
ARRIVaL - Artificial Rupture of membranes versus Repeat Intra-Vaginal prostaglandins for induction of labour: a randomised controlled trial ACTRN12613000370707 Mater Mothers` Research Centre, Mater Health Services michael.beckmann@mater.org.au Recruitment complete Labour and intrapartum care
BAC - Birth after Caesarean. Planned vaginal birth or planned caesarean section for women at term with a single previous caesarean birth ISRCTN53974531/NHMRC349460 Maternal Perinatal Clinical Trials Unit, Adelaide Women's and Children's
Pat Ashwood		 Recruitment complete Labour and intrapartum care Women with a single prior caesarean presenting in their next pregnancy with a single live fetus in cephalic presentation who have reached 37 weeks gestation, and who don't have a contraindication to a planned VBAC.
PROGRESS - Australian Collaborative trial of vaginal progesterone for prevention of neonatal respiratory distress syndrome ISRCTN20269066; NHMRC399137 Maternal Perinatal Clinical Trials Unit, Adelaide Women's and Children's Pat Ashwood Recruitment complete Preterm birth ? prevention and treatment. Preterm birth ? improving outcomes (antenatal interventions). Newborn respiratory Pregnant women with a history of prior spontaneous preterm birth at less than 34 weeks gestation
EECV2 - Early external cephalic version 2 trial PT0542/ISRCTN56498577 McMaster, Canada Eileen Hutton Recruitment complete Models of care
InFANT - The Infant Feeding Activity and Nutrition Trial an early intervention to prevent childhood obesity: cluster-randomised controlled trial ISRCTN81847050 Melbourne Dr Karen Campbell Recruitment complete Newborn nutrition
PneuMum - Pneumococcal Vaccination of Australian Indigenous Mothers to See if it Protects their babies from Ear Disease NCT00310349; NCT00714064 Menzies School of Health Research Amanda Leach Recruitment complete
A family tobacco control program to reduce respiratory illness in Indigenous infants. ACTRN12609000397213 Menzies School of Health Research/Royal Darwin Hospital Vanessa Johnston Recruitment complete Smoking in pregnancy. Indigenous maternal/perinatal health
Weighing pregnant women to achieve ideal weight gains in pregnancy ACTRN12607000272493 Mercy Hospital Recruitment complete Obesity
Randomised controlled trial to compare heated humidified high-flow nasal cannulae with nasal continuous positive airway pressure postextubation in premature infants Mercy Hospital for Women c.collins@mercy.com.au Recruitment complete
DAME - Diabetes & antenatal milk expressing: a pilot/feasibility study Mercy Hospital for Women Kerri McEgan Recruitment complete